Projects
Persistent T-cell dysfunction in synergistic VL-HIV co-infection Institute of Tropical Medicine
Consequences of Mycobacterium tuberculosis genetic diversity in the context of HIV co-infection for laboratory diagnosis of tuberculosis in Africa Institute of Tropical Medicine
1. To determine the variation and risk factors for drug-resistant tuberculosis in sub-Saharan Africa.
2. To evaluate the clinical utility of a novel molecular assay in various combinations with existing methods for diagnosis of HIV-related tuberculosis.
3. To determine the clinical predictors of mycobacteremia among HIV-infected smear- negative adults in a high prevalence HIV/TB setting in relation to the utility of ...
European and South African HIV co-infection research consortium Institute of Tropical Medicine
The overall aim of the proposed staff exchange program is to establish a long lasting collaboration between South African and European research teams involved in HIV co-infection research. This effort ultimately should lead to new ways to improve the care/treatment for patients with HIV co-infections and to decrease the high mortality among persons with HIV infection in Africa.
South Africa is the country with the largest number ...
European and South African HIV co-infection research consortium (ESAHIV coinfRes). University of Antwerp
Assessment of vaccine efficacy for Malaria and Tuberculosis in a co-infection setting relevant for disease endemic sub-Saharan African regions. Vrije Universiteit Brussel
Nontuberculous mycobacteria pulmonary disease and tuberculosis-nontuberculous mycobacteria co-infection: Epidemiology, diagnosis, and management at a tertiary health facility in Ghana Institute of Tropical Medicine
Impact of early-life multi-mycotoxin exposure on B cells epigenetic profile and infection by oncogenic viruses: unravelling interaction with immune-regulatory cytokines profiles & co-infections in young children Ghent University
Oncogenic viruses play an essential role in carcinogenesis. Chronic dietary intakes of multiple mycotoxins are hypothesized to be associated and interact with these viruses to enhance the risk of developing juvenile carcinomas. In this proposal we focus on infection by the Eppstein-Barr virus (EBV), which is linked to childhood Burkitt’s lymphoma, and endemic in parts of sub-Saharan Africa, where EBV and chronic mycotoxin exposure co-exist. ...