Targeted detection of nucleic acid mutations for improved lung cancer diagnostics in liquid biopsies KU Leuven
In this project we aimed to improve the current molecular diagnostics approaches for lung cancer- related mutation detection in liquid biopsies. Liquid biopsy refers to sampling and analysis of biological fluids—typically blood—and has potential for screening, diagnosis, predicting and monitoring of treatment response. However, current assays based on circulating tumor DNA (DNA released by tumor cells in the blood) suffer from sensitivity ...