Researcher
Max Mazzone
- Disciplines:Morphological sciences, Oncology
Affiliations
- Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → Today
Projects
1 - 10 of 54
- Tricking tumor immunosuppression: RNA epigenetics as novel target to improve cancer immunotherapyFrom1 Jan 2022 → TodayFunding: FWO EOS
- Duchenne muscular dystrophy.From1 Jan 2022 → TodayFunding: Nonprofit institution or equivalents
- Characterizing the epigenetic features of tumor-associated macrophagesFrom19 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Preclinical validation of next generation immunomodulatory drugs in combination with immune checkpoint inhibitorsFrom19 Oct 2021 → TodayFunding: Foundations, funds and other with scientific goal
- DIPITO: valorisation of deep immune profiling and novel immunotherapeutics for oncology.From1 Oct 2021 → TodayFunding: IOF - mandates
- Expression of the metabolite transporter SLC4A4 in pancreatic cancer cells promotes immuneescape and resistance to immunotherapyFrom1 Oct 2021 → TodayFunding: IOF - technology validation in lab
- The neurovascular link: an unexpectedly important role of metabolism.From1 Oct 2021 → TodayFunding: BOF - Methusalem
- Macrophage metabolic reprogramming as a therapeutic approach for cancer and muscular dystrophyFrom1 Jul 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Arachidonic acid metabolism, a cross point between "bad" and "good" macrophages in cancer: a novel therapeutic perspective?From1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Integration of complementary, high throughput single-cell omics with spatial resolution.From1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
1 - 10 of 160
- PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.(2022)
Authors: Margherita Demicco, Ginevra Doglioni, Anke Vandekeere, Juan Fernandez Garcia, David Nittner, Francesca Rizzollo, Panagiotis Karras, Dorien Broekaert, Sofie Demeyer, Ayse Bassez, et al.
Pages: 747 - 753 - PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index(2022)
Authors: Britt Van Renterghem, Peter Pokreisz, Carla Riera Domingo, Agnieszka Wozniak, Massimiliano Mazzone, Patrick Schöffski
Pages: 568 - 581Number of pages: 14 - Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia(2022)
Authors: Massimiliano Mazzone
Number of pages: 18 - Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes(2022)
Authors: Massimiliano Mazzone, Peter Carmeliet
Number of pages: 22 - Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer(2022)
Authors: Ward Celus, Silvia Rivis, Ewout Landeloos, Yannick Van Herck, Abhishek Garg, Jean-Christophe Marine, Mario di Matteo, Oliver Bechter, Massimiliano Mazzone
Pages: 126 - 141Number of pages: 16 - Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1 alpha Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2(2021)
Authors: Massimiliano Mazzone
Pages: 1849 - 1861Number of pages: 13 - Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function(2021)
Authors: Massimiliano Mazzone
Pages: 1071 - 1090Number of pages: 20 - N-acetylaspartate release by glutaminolytic ovarian cancer cells sustains protumoral macrophages(2021)
Authors: Massimiliano Mazzone
Number of pages: 16 - Cryptic transcripts: the masked heroes that break tumor immunotolerance and rescue the immunotherapy response(2021)
Authors: Laurien Van Dyck, Diether Lambrechts, Massimiliano Mazzone, Bernard Thienpont
- Isolation and separation of murine tumor-associated macrophages (TAMs) subpopulations from orthotopic 4T1 breast tumors.(2021)
Authors: Carla Riera Domingo, Massimiliano Mazzone
Pages: 100481