Deciphering the mechanism of extracellular vesicle entry into the brain via the blood-cerebrospinal fluid barrier and possible applications as innovative brain targeting strategy. Ghent University
Peripheral blood is separated from the brain by the presence of central nervous system (CNS)
barriers. These barriers are essential for brain homeostasis, but are also responsible for the
inability of many therapeutic molecules to enter the brain. The blood-cerebrospinal fluid (CSF) CNS
barrier forms a unique interface between blood and CSF and is composed of a single layer of
cuboidal choroid ...