Organisation
Laboratory of Intensive Care Medicine
Division
The overall research objective of the Laboratory of Intensive Care Medicine is to unravel key pathways underlying critical illness-induced organ failure, thereby identifying potential therapeutic targets to enhance recovery. We focus on endocrine and metabolic underlying mechanisms of organ-specific problems evoked by critical illness.
Current researchers
1 - 10 of 32 results
- Greta Van den Berghe (Responsible)
- Giorgia Carra (Member)
- Michaël Casaer (Member)
- Grégoire Coppens (Member)
- Dieter Dauwe (Member)
- Astrid De Bruyn (Member)
- Veerle De Sloovere (Member)
- Yves Debaveye (Member)
- Jasperina Dubois (Member)
- Chloë Goossens (Member)
Projects
1 - 10 of 68 results
- Ketone body supplementation as a new therapy for ICU-acquired weaknessFrom15 May 2020 → TodayFunding: BOF - various
- Impact of acute and possibly permanent neuro-endocrine changes on critical illness induced muscle weakness and its legacyFrom1 Jan 2020 → TodayFunding: FWO research project
- Big data for knowledge discovery and prediction in the intensive care unitFrom1 Oct 2019 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Machine Learning applied to Intensive Care MedicineFrom16 Oct 2018 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- EFFECTS trial: assessing the influence of timing of Enteral Feeding support in Esophageal Cancer patients on muscle functTION and SurvivalFrom1 Oct 2018 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Survival of the Fittest: On how to enhance recovery from critical illness through learning from evolutionary conserved catabolic pathwaysFrom1 Oct 2018 → TodayFunding: H2020 - Frontier Research (ERC)
- Leveraging data-driven models into decision support applications in the intensive care unitFrom1 Oct 2018 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Dynamic impact of critical illness and associated treatments on the long-term outcome of children: a quest for underlying molecular mechanisms.From1 May 2018 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Intensive care extended beyond the “adaptive” time window: from impact on the adrenocortical ‘fight or flight’ response towards a possible new treatmentFrom1 Jan 2018 → TodayFunding: FWO research project
- Optimization of ketone body supplementation to protect against ICU-acquired weaknessFrom1 Jan 2018 → 31 Dec 2018Funding: BOF - Other initiatives
Publications
1 - 10 of 666 results
- Establishing a Unified COVID-19 “Immunome”: Integrating Coronavirus Pathogenesis and Host Immunopathology(2020)Journal: Frontiers in ImmunologyVolume: 11
Authors: Els Wauters, Karin Thevissen, Carine Wouters, Francesca Maria Bosisio, Frederik De Smet, Jan Gunst, Stephanie Humblet-Baron, Diether Lambrechts, Adrian Liston, Patrick Matthys, et al.
Pages: 1642 - 1642 - Long-term developmental effect of withholding parenteral nutrition in paediatric intensive care units: a 4-year follow-up of the PEPaNIC randomised controlled trial.(2020)Journal: Lancet Child Adolesc HealthISSN: 2352-4642Issue: 7Volume: 4
Authors: An Jacobs, Karolijn Dulfer, Renate D Eveleens, José Hordijk, Hanna Van Cleemput, Ines Verlinden, Pieter J Wouters, Liese Mebis, Gonzalo Garcia Guerra, Koen Joosten, et al.
Pages: 503 - 514 - Can augmented renal clearance be detected using estimators of glomerular filtration rate?(2020)Journal: Critical CareISSN: 1364-8535Issue: 1Volume: 24
Authors: Matthias Gijsen, Peter Alexander Wilmer, Geert Meyfroidt, Joost Wauters, Isabel Spriet
Number of pages: 4 - Health-related quality of life of children and their parents 2 years after critical illness: pre-planned follow-up of the PEPaNIC international, randomized, controlled trial.(2020)Journal: Critical CareISSN: 1364-8535Issue: 1Volume: 24
Authors: José Hordijk, Sascha Verbruggen, Ilse Vanhorebeek, Fabian Güiza, Pieter Wouters, Greta Van den Berghe, Koen Joosten, Karolijn Dulfer
Pages: 347 - Predicting patient nurse-level intensity for a subsequent shift in the intensive care unit: A single-centre prospective observational study.(2020)Journal: International Journal of Nursing StudiesISSN: 0020-7489Volume: 109
Authors: Karen Decock, Michaël Casaer, Fabian Guïza, Pieter Wouters, Mieke Florquin, Peter Alexander Wilmer, Stefan Janssens, Sandra Verelst, Greta Van den Berghe, Luk Bruyneel
Pages: 103657 - Towards a fasting-mimicking diet for critically ill patients: the pilot randomized crossover ICU-FM-1 study(2020)Journal: Critical CareISSN: 1364-8535Issue: 1Volume: 24
Authors: Lisa Van Dyck, Ilse Vanhorebeek, Peter Alexander Wilmer, An Schrijvers, Inge Derese, Liese Mebis, Pieter J Wouters, Greta Van den Berghe, Jan Gunst, Michaël Casaer
Number of pages: 12 - Determinants of Total/ionized Calcium in patients undergoing citrate CVVH: A retrospective observational study.(2020)Journal: Journal of Critical CareISSN: 0883-9441Volume: 59
Authors: Willem Boer, Mathias van Tornout, Francesca Solmi, Xavier Willaert, Maria Schetz, Heleen Oudemans-van Straaten
Pages: 16 - 22 - Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine.(2020)Journal: Critical CareISSN: 1364-8535Issue: 1Volume: 24
Authors: Annika Reintam Blaser, Jean-Charles Preiser, Sonja Fruhwald, Peter Alexander Wilmer, Jan Wernerman, Carina Benstoem, Michaël Casaer, Joel Starkopf, Arthur van Zanten, Olav Rooyackers, et al.
Pages: 224 - Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver(2020)Journal: Molecular Systems BiologyISSN: 1744-4292Issue: 5Volume: 16
Authors: Vanessa Dubois, Celine Gheeraert, Wouter Vankrunkelsven, Julie Dubois-Chevalier, Helene Dehondt, Marie Bobowski-Gerard, Manjula Vinod, Francesco Paolo Zummo, Fabian Guiza, Maheul Ploton, et al.
Number of pages: 27 - A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC)(2020)Journal: Intensive Care MedicineISSN: 0342-4642Issue: 5Volume: 46
Authors: Randall Chesnut, Sergio Aguilera, Andras Buki, Eileen Bulger, Giuseppe Citerio, D Jamie Cooper, Ramon Diaz Arrastia, Michael Diringer, Anthony Figaji, Guoyi Gao, et al.
Pages: 919 - 929Number of pages: 11