Organisation
Laboratory of Intensive Care Medicine
Division
The overall research objective of the Laboratory of Intensive Care Medicine is to unravel key pathways underlying critical illness-induced organ failure, thereby identifying potential therapeutic targets to enhance recovery. We focus on endocrine and metabolic underlying mechanisms of organ-specific problems evoked by critical illness.
Current researchers
1 - 10 of 51 results
- Greta Van den Berghe (Responsible)
- Mirna Bastos Marques (Member)
- Eva Boonen (Member)
- Giorgia Carra (Member)
- Michaël Casaer (Member)
- Grégoire Coppens (Member)
- Dieter Dauwe (Member)
- Astrid De Bruyn (Member)
- Veerle De Sloovere (Member)
- Erwin De Troy (Member)
Projects
1 - 10 of 77 results
- Antibacterial dose optimisation based on augmented renal clearance in adult critically ill patients and selected pediatric patientsFrom1 Oct 2021 → TodayFunding: BOF - postdoctoral mandates
- Impact of duration of critical illness on cholesterol availability in relation to outcomeFrom1 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Improving our understanding of respiratory muscle training to facilitate weaning from mechanical ventilation in the ICU.From1 Jan 2021 → TodayFunding: FWO research project
- Impact of duration of critical illness on cholesterol availability in relation to outcomeFrom1 Jan 2021 → TodayFunding: FWO research project
- Modelling Cerebrovascular Autoregulation Lab Animal Data to Build a Patient Autoregulation MonitorFrom23 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Impact of metabolic interventions on atrial fibrillation during critical illness: focus on tight glucose control with insulin and early macronutrient availability.From20 Oct 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Calming the storm: treating hypercoagulability and hyperinflammation in patients with COVID-19From22 May 2020 → 21 May 2021Funding: FWO Applied Biomedical Research (TBM)
- Ketone body supplementation as a new therapy for ICU-acquired weaknessFrom15 May 2020 → TodayFunding: BOF - various
- Impact of acute and possibly permanent neuro-endocrine changes on critical illness induced muscle weakness and its legacyFrom1 Jan 2020 → TodayFunding: FWO research project
- Bacteriophage therapy for difficult-to-treat infections: the implementation of a multidisciplinary phage task force (PHAGEFORCE)From14 Nov 2019 → TodayFunding: BOF - projects
Publications
1 - 10 of 778 results
- Altered cholesterol homeostasis in critical illness-induced muscle weakness: effect of exogenous 3-hydroxybutyrate.(2021)
Authors: Chloë Goossens, Ruben Weckx, Sarah Derde, Sarah Vander Perre, Inge Derese, Paul Van Veldhoven, Bart Ghesquière, Greta Van den Berghe, Lies Langouche
Pages: 252 - Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity.(2021)
Authors: Lore Vanderbeke, P Van Mol, Yannick Van Herck, Frederik De Smet, S Humblet-Baron, Kimberly Martinod, A Antoranz, Ingrid Arijs, B Boeckx, Francesca Maria Bosisio, et al.
Pages: 4117 - 4117 - Proceedings of the First Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness.(2021)
Authors: Jan Claassen, Yama Akbari, Sheila Alexander, Mary Kay Bader, Kathleen Bell, Thomas P Bleck, Melanie Boly, Jeremy Brown, Sherry H-Y Chou, Michael N Diringer, et al.
Pages: 4 - 23 - Endocrine Interventions in the ICU(2021)
Authors: Lies Langouche, Greta Van den Berghe, Dick Swaab, Ruud M Buijs, Felix Kreier, Paul J Lucassen, Ahmed Salehi
Pages: 1 - 548 - Intracranial pressure monitoring in patients with acute brain injury in the intensive care unit (SYNAPSE-ICU): an international, prospective observational cohort study.(2021)
Authors: Chiara Robba, Francesca Graziano, Paola Rebora, Francesca Elli, Carlo Giussani, Mauro Oddo, Geert Meyfroidt, Raimund Helbok, Fabio S Taccone, Lara Prisco, et al.
Pages: 548 - 558 - Corrigendum to "itraconazole for COVID-19: Preclinical studies and a proof-of-concept randomized clinical trial Laurens".(2021)
Authors: Laurens Liesenborghs, Isabel Spriet, Dirk Jochmans, Ann Belmans, Iwein Gyselinck, Laure-Anne Teuwen, Sebastiaan ter Horst, Erwin Dreesen, Tatjana Geukens, Matthias M Engelen, et al.
Pages: 103454 - Long-term legacy of critical illness: mechanisms and clinical impact(2021)
Authors: Nathalie Van Aerde, Greet Hermans, Ilse Vanhorebeek
- Fluconazole Underexposure in Critically Ill Patients: a Matter of Using the Right Targets?(2021)
Authors: Ruth Van Daele, Yves Debaveye, Katrien Lagrou, Isabel Spriet
Number of pages: 2 - Meropenem Pharmacokinetics and Target Attainment in Critically Ill Patients Are Not Affected by Extracorporeal Membrane Oxygenation: A Matched Cohort Analysis(2021)
Authors: Matthias Gijsen, Erwin Dreesen, Pieter Annaert, Johan Nicolai, Yves Debaveye, Joost Wauters, Isabel Spriet
Number of pages: 12 - Targeted treatment of iron deficiency in prolonged critical illness: an opportunity to improve survival or not?Y(2021)
Authors: Jan Gunst, Greta Van den Berghe, Michaël Casaer
Number of pages: 3