Projects
Investigating the role of peripheral nerve stimulation in mediating noninvasive neuromodulation effects in healthy volunteers KU Leuven
Noninvasive brain stimulation (NIBS) methods hold great promise for treating a wide range of neurological and psychiatric disorders. However, reported effects are often small, difficult to reproduce and the basic mechanisms underpinning them are not clear. It is widely assumed that effects of NIBS are solely caused by the electric field that it generates in the brain. However, NIBS also generate an electric field in the scalp. These fields ...
Cholinergic and noradrenergic neuromodulation of memory and mood. University of Antwerp
Offline learning during low-frequency rTMS intervention: effect on neuromodulation of cortical functions gauged with fMRI and EEG KU Leuven
Co-localization and neuromodulation of interoceptive and emotional processes in the insular cortex. KU Leuven
Contrary to classical doctrines, our daily introspective experience, and clinical and scientific evidence, indicate that inner bodily signals substantiate emotions and intimately shape cognition. The anterior insular cortex (AIC), a prime target in neuropsychiatric disorders, recently emerged as a crucial interface between sensory inputs related to bodily physiology (i.e. interoception) and emotional and cognitive processes underlying ...
Novel acoustic tools for neuromodulation KU Leuven
Ultrasound is an emerging new tool for non-invasive neuromodulation. The recent major advances in the field have led to ongoing clinical trials to asses ultrasound as a treatment for ao. Essential tremor, Alzheimer's and Parkinson's disease. Nevertheless, the mechanism remains largely unknown and quantitative information is still lacking. An in-house state-of-the-art high-density CMOS MEA provides a unique opportunity to fill these gaps which ...
Advancements in neuromodulation. University of Antwerp
Epicranial cortical stimulation: development and evaluation of a novel, minimally invasive, neuromodulation method KU Leuven
Invasive cortical stimulation (ICS) is an neuromodulation method in which electrodes are implanted on the cortex to deliver chronic stimulation. ICS has been used to treat neurological disorders such as neuropathic pain, movement disorders and tinnitus. A significant disadvantage of ICS is its highly invasive nature. Noninvasive neuromodulation methods such as transcranial magnetic stimulation and transcranial current stimulation show great ...
The role of non-cholinergic neurons in cholinergic neuromodulation. University of Antwerp
Integrated Platform for Closed-Loop Motor Training and Adaptive Neuromodulation KU Leuven
Perception, action and cognition are critical to engage in daily motor tasks such as buttoning a shirt or moving objects. These tasks are challenged as a result of aging and dramatically affected in case of cerebrovascular accidents or neurodegenerative diseases. Accordingly, it is critical to investigate the overarching principles governing the control and (re)learning of movements in health and disease across the lifespan. Therefore, the ...