Organisations
Centre for Molecular and Vascular Biology KU Leuven
The Center for Molecular and Vascular Biology performs research related to the following topics:- Pathogenesis of thrombosis and bleeding. - Development of assays for the diagnosis of thrombosis and bleeding. – Signalling and transcription factor regulation in megakaryocytes and platelets. - Genetics for bleeding and thrombotic disorders. –(patho)physiology of megakaryopoiesis. – Role of transcription factors in endothelial heterogeneity. – ...
Laboratory for Molecular Cancer Biology (VIB-KUÂ Leuven) KU Leuven
The research program of the Laboratory for Molecular Cancer Biology is devoted to the analysis of pathways governing the genesis, progression and maintenance of cancer.Our current research efforts follow from our recent studies on the p53 tumor suppressor. p53 is a transcription factor that functions as a central component of most cellular stress responses. The outcome of p53-mediated surveillance is closely dependent on the type of stress ...
Laboratory of Molecular Biology of Leukemia (VIB-KUÂ Leuven) KU Leuven
The Laboratory of Molecular Biology of Leukemia tries to understand the genetic complexity of leukemia, with the aim to use that information to develop novel treatment strategies.
Leukemia is a genetically complex disease that is characterized by the accumulation of abnormal blood cells. The leukemia cells often harbor chromosomal defects and additional more sublte changes (mutations) in their genome. This information is used for ...
Biochemistry, Molecular and Structural Biology KU Leuven
Research on four types of functionally active proteins - Copper proteins : hemocyanins (involved in dioxygen binding). - Thiol proteins: metallothioneins (metal detoxication and donation). - Protease inhibitors: alpha -2-macroglobulin homologues. - Regulatory proteins: cytokines (defencesystems against infection). Aim: to determine, after their isolation or possible induction, the composition and the primary to quaternary structure of these ...
Pharmaceutical Biotechnology and Molecular Biology Vrije Universiteit Brussel
MICH develops research in the following areas: 1. Fundamental research on the replication cycle of poliovirus, research concentrates on the first steps of the cycle (adsorption, uncoating) and the last step (assembly); 2. Development of new poliovaccines (also biotech vaccines); 3. Fundamental research on antiviral compounds (in collaboration with Janssen Research Foundation); 4. Viruses on the origin of multiple sclerosis?; 5. Theiler murine ...
Molecular Virology and Gene Therapy KU Leuven
The division Molecular Virology and Gene Therapy aims at developing novel therapeutics and diagnostics starting from basic research into the molecular cause of disease and employing the most advanced biomedical technologies. Research can be basic, applied or technological; in all cases our research aims at future applications in medicine.
Major disease areas are AIDS and Parkinson's disease. Other interests are gene therapy of cystic ...
Laboratory of cell biology and histology University of Antwerp
Follicle Biology Vrije Universiteit Brussel
Basic aims of the Follicle Biology Laboratory, led by Prof. Ellen Anckaert are the design and validation of new culture systems for ovarian follicles and unripe egg cells to establish practical, applicable strategies for fertility clinics.
Fundamental and pre-clinical research:
1) optimization of multistep systems for in vitro follicle activation, growth and maturation: mouse in vitro models for culturing ovarian follicles ...
Structural Biology Brussels Vrije Universiteit Brussel
Structural biology is a central discipline in molecular life sciences, and our Center for Structural Biology (CSB) has been a cornerstone of the research conducted at the VUB and the VIB, first under the leadership of Lode Wyns, and more recently under the guidance of Jan Steyaert and Han Remaut. The Center has made several top-tier discoveries, of which Nanobody technology has been running like a tread through the history of CSB. The centre ...