Projects
Influence of type and place of distal colon descendence and rectum in humans for evaluation of medication efficiency in modeling sensory and motor responses. KU Leuven
Aim of the project is to compare the sensory-motor response of the distal colon and of the rectum to different kinde of distensions and to evaluate the effect of linaclotide on these responses in healthy subjects and in IBS patients.
Parallel evolution and eco-evolutionary dynamics in city ponds – from evolution to nature-based solutions in coupled human-natural systems KU Leuven
There has been an upsurge in studies on adaptive evolution in cities over the past five years because of its high relevance in the context of population resilience and persistence, and the need to improve biodiversity conservation across anthropogenic landscapes. This proposal builds on the exceptionally well-documented multi-trait urban evolution in water fleas (Daphnia) in Flanders. I aim to address a number of key knowledge gaps in the ...
Evolution and ecology of zoonotic wildlife pathogens. University of Antwerp
Evolution, philosophy and cultural diversity. KU Leuven
Towards a mechanistic understanding of the emergence, evolution, acquisition and processing of human-like languages in populations of autonomous agents Vrije Universiteit Brussel
ESSENCE: Evolution of Shared Semantics in Computational Environments. Vrije Universiteit Brussel
...
Charting non-small cell lung cancer evolution and heterogeneity through multi-omics analysis and deconvolution KU Leuven
n many malignancies, molecular and cellular heterogeneity poses major challenges for diagnosis and treatment. Tumours are composed of subpopulations of cells harbouring distinct genomic alterations (subclones) which can affect their phenotype. Studies of intra-tumour heterogeneity generally focus on a single information layer. However, multi-omics characterisation is required to shed light on the functional impact of subclonal mutations. ...
Characterization of hepatitis C virus infected B-lymphocytes and their impact on the evolution of acute infection and therapy outcome Ghent University
Worldwide an estimated 170 million people are chronically infected with the hepatitis C virus (HCV) and, after decades, have a significant risk at developing severe liver disease and liver cancer. Until recently therapy was accompanied with severe side effects and efficacies ranged from 50 to 70%. Recently HCV-specific direct antiviral agents increased efficacy rates to above 95% for most infected individuals. However, these therapies are ...