Projects
Regulation of endocardial cell plasticity during embryonic heart valve development and maturation through BMP SMAD KU Leuven
Congenital heart diseases (CHDs) are the most common birth defects, with nearly a third involving heart valve defects. During the last decade, it has become increasingly clear that the Bone Morphogenetic Protein (BMP) and Notch-mediated signaling cascades are both key regulators of embryonic and postnatal heart valve development as well as adult valve pathogenesis. Disruption of their signaling has been linked to valve defects in animal ...
Cell-cell communication during maturation and cryopreservation of immature oocytes in the cat and the ox Ghent University
The domestic cat (Felis catus) is considered as a practical and valuable model to study assisted reproductive technologies (ART). Techniques that can be considered as ART are artificial insemination, in vitro embryo production consisting of in vitro maturation, in vitro fertilization
or intracytoplasmic sperm injection and in vitro culture, embryo transfer, cryopreservation of sperm, oocytes and embryos which would provide an accessible ...
Deep phenotyping of cellular heterogeneity and maturation in human iPSC-derived brain organoids and cardiomyocytes. University of Antwerp
Injury incidence and patterns in U10-U14 soccer players within Belgian football academies: A prospective cohort study examining the risk and/or protective factors associated with growth, maturation, physical fitness and motor coordination. Vrije Universiteit Brussel
The journey of a memory: dynamics of learning and consolidation in maturation and ageing KU Leuven
"We are our memory". The MEMODYN project investigates this fascinating subject of fundamental importance. We take a fresh perspective that emphasises the study of memory, in its natural dynamic setting, as a journey in the making. The two key characters in this journey are learning and consolidation; these processes are known to interact but have hitherto been studied in isolation. The perspective of this project enables them to be ...
The journey of a memory: dynamics of learning and consolidation in maturation and ageing Ghent University
"We are our memory". The MEMODYN project investigates this fascinating subject of
fundamental importance. We take a fresh perspective that emphasises the study of memory,
in its natural dynamic setting, as a journey in the making. The two key characters in this
journey are learning and consolidation; these processes are known to interact but have
hitherto been studied in isolation. The perspective of this project ...
Advanced Solutions for Neonatal Sleep Analysis and the Effects of Maturation KU Leuven
Worldwide approximately 11% of the babies are born before 37 weeks of gestation. The survival rates of these prematurely born infants have steadily increased during the last decades as a result of the technical and medical progress in the neonatal intensive care units (NICUs). The focus of the NICUs has therefore gradually evolved
from increasing life chances to improving quality of life. In this respect, promoting and supporting optimal ...
Uncovering the role of iron metabolism in beta cell differentiation, maturation, and function. Vrije Universiteit Brussel
for glycemic control but fails to tackle the underlying beta cell defect.
Transplantation of pancreatic islets has shown that cell therapy can
result in insulin independence, but donor islets are scarce. Stem cellderived beta cells (SC-beta) may offer a reliable cell source for
transplantation. However, improved understanding of beta cell
...
Deciphering the involvement of iron metabolism in beta cell differentiation, maturation, and function. Vrije Universiteit Brussel
chronic hyperglycemia. Today’s treatments ensure glycemic control
but fail to tackle the underlying beta cell defect. Although cell therapy
via transplantation of islets of Langerhans can result in insulin
independence, donor islets remain scarce. Stem cell derived beta
cells (SC-beta) may offer an alternative and abundant cell source for
...