Publications
Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses KU Leuven
Novel indolylarylsulfone derivatives as covalent HIV-1 reverse transcriptase inhibitors specifically targeting the drug-resistant mutant Y181C KU Leuven
'We had to manage what we had on hand, in whatever way we could': adaptive responses in policy for decentralized drug-resistant tuberculosis care in South Africa Institute of Tropical Medicine
In 2011, the South African National TB Programme launched a policy of decentralized management of drug-resistant tuberculosis (DR-TB) in order to expand the capacity of facilities to treat patients with DR-TB, minimize delays to access care and improve patient outcomes. This policy directive was implemented to varying degrees within a rapidly evolving diagnostic and treatment landscape for DR-TB, placing new demands on already-stressed health ...
Psychometric evaluation of a new drug-resistant tuberculosis stigma scale Institute of Tropical Medicine
OBJECTIVES: Stigma contributes to diagnostic delay, disease concealment, and reduced wellbeing for people with multidrug-resistant tuberculosis (MDR-TB) and their communities. Despite the negative effects of stigma, there are no scales to measure stigma in people with MDR-TB. This study aimed to develop and validate a scale to measure stigma in people affected by MDR-TB in Vietnam.
STUDY DESIGN AND SETTING: People with ...
Depression, stigma and quality of life in people with drug-susceptible TB and drug-resistant TB in Vietnam Institute of Tropical Medicine
BACKGROUND: Drug resistance poses a major barrier to global control of TB - a leading infectious cause of death. Depression and stigma occur commonly among people with TB. However, the relationship between drug-resistant forms of TB, depression and stigma are not well understood.
OBJECTIVE : To compare depression, stigma and health-related quality of life (HRQoL), among people with drug-susceptible TB (DS-TB) and multidrug-resistant ...
Discovery of Antiseizure Compounds in Zebrafish Models for the Treatment of Drug-Resistant Epilepsy KU Leuven
European Expert Opinion on ANT-DBS therapy for patients with drug-resistant epilepsy (a Delphi consensus) Ghent University KU Leuven
Targeted next-generation sequencing of sputum for diagnosis of drug-resistant TB; results of a national survey in Democratic Republic of the Congo Institute of Tropical Medicine University of Antwerp KU Leuven
The surveillance of drug resistance among tuberculosis (TB) patients is central to preventing the spread of antimicrobial resistance. The Democratic Republic of the Congo (DR Congo) is classified by the World Health Organization (WHO) as a country with a high burden of TB and multidrug-resistant TB (MDR-TB), but there are no nationally representative data on drug resistance. In 2016-2017, a national survey of TB patients was conducted in 108 ...