Researcher
Erik De Clercq
- Keywords:Medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → 30 Sep 2013
Publications
1 - 10 of 447 results
- Pharmacophore-fusing design of pyrimidine sulfonylacetanilides as potent non-nucleoside inhibitors of HIV-1 reverse transcriptase(2020)Journal: Bioorganic ChemistryISSN: 0045-2068Volume: 96
Authors: Yali Sang, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang, Fener Chen
Number of pages: 11 - Therapeutic options for the 2019 novel coronavirus (2019-nCoV)(2020)Journal: Nature Reviews. Drug DiscoveryISSN: 1474-1776Issue: 3Volume: 19
Authors: Guangdi Li, Erik De Clercq
Pages: 149 - 150Number of pages: 2 - Rapidly decreased HBV RNA predicts responses of pegylated interferons in HBeAg-positive patients: a longitudinal cohort study(2020)Journal: Hepatology InternationalISSN: 1936-0533Issue: 2Volume: 14
Authors: Min Zhang, Guangdi Li, Jia Shang, Chen Pan, Minxiang Zhang, Zhibiao Yin, Qing Xie, Yanzhong Peng, Qing Mao, Xinqiang Xiao, et al.
Pages: 212 - 224Number of pages: 13 - Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel(2020)Journal: Journal of Medicinal ChemistryISSN: 0022-2623Issue: 3Volume: 63
Authors: Dongwei Kang, F Xavier Ruiz, Da Feng, Alyssa Pilch, Tong Zhao, Fenju Wei, Zhao Wang, Yanying Sun, Zengjun Fang, Erik De Clercq, et al.
Pages: 1298 - 1312Number of pages: 15 - Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors(2020)Journal: Acta Pharmaceutica Sinica BISSN: 2211-3835Issue: 2Volume: 10
Authors: Kaijun Jin, Minjie Liu, Chunlin Zhuang, Erik De Clercq, Christophe Pannecouque, Ge Meng, Fener Chen
Pages: 344 - 357Number of pages: 14 - Clinical significance of chemokine receptor antagonists(2020)Journal: Expert Opinion on Drug Metabolism and ToxicologyISSN: 1742-5255Issue: 1Volume: 16
Authors: Miao Miao, Erik De Clercq, Guangdi Li
Pages: 11 - 30Number of pages: 20 - Ligand-Based Design of Nondimethylphenyl-Diarylpyrimidines with Improved Metabolic Stability, Safety, and Oral Pharmacokinetic Profiles(2019)Journal: Journal of Medicinal ChemistryISSN: 0022-2623Issue: 24Volume: 62
Authors: Yali Sang, Sheng Han, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang, Fener Chen
Pages: 11430 - 11436Number of pages: 7 - Overview of Recent Strategic Advances in Medicinal Chemistry(2019)Journal: Journal of Medicinal ChemistryISSN: 0022-2623Issue: 21Volume: 62
Authors: Gaochan Wu, Tong Zhao, Dongwei Kang, Jian Zhang, Yuning Song, Vigneshwaran Namasivayam, Jacob Kongsted, Christophe Pannecouque, Erik De Clercq, Vasanthanathan Poongavanam, et al.
Pages: 9375 - 9414Number of pages: 40 - Molecular design opportunities presented by solvent-exposed regions of target proteins(2019)Journal: Medicinal Research ReviewsISSN: 0198-6325Issue: 6Volume: 39
Authors: Xiangyi Jiang, Ji Yu, Zhongxia Zhou, Jacob Kongsted, Yuning Song, Christophe Pannecouque, Erik De Clercq, Dongwei Kang, Vasanthanathan Poongavanam, Xinyong Liu, et al.
Pages: 2194 - 2238Number of pages: 45 - Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H, 3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase(2019)Journal: Bioorganic & Medicinal ChemistryISSN: 0968-0896Issue: 17Volume: 27
Authors: Ping Gao, Xiqiang Cheng, Lin Sun, Shu Song, Mar Alvarez, Joanna Luczkowiak, Christophe Pannecouque, Erik De Clercq, Luis Menendez-Arias, Peng Zhan, et al.
Pages: 3836 - 3845Number of pages: 10