Researcher
Christophe Pannecouque
- Keywords:Medicine
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Jul 2002 → Today
Projects
1 - 3 of 3 results
- An automated platform for multiparameter data collection on live pathogens of higher or unknown biosafety risk.From26 Jun 2014 → 31 Dec 2018Funding: Hercules - Large scale research infrastructure
- Identification of biomarkers and new therapeutic targets in HTLV-1-associated pathologies.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
- Mechanistic study on virus entry and replication. A fundamental approach to the development of new and specific antiviral chemotherapeutics.From1 Jan 2010 → 31 Dec 2014Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 286 results
- Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs(2019)Journal: Bioorganic & Medicinal ChemistryISSN: 0968-0896Issue: 3Volume: 27
Authors: Zhao Wang, Zhao Yu, Dongwei Kang, Jian Zhang, Ye Tian, Dirk Daelemans, Erik De Clercq, Christophe Pannecouque, Peng Zhan, Xinyong Liu
Pages: 447 - 456Number of pages: 10 - From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors(2019)Journal: Journal of Enzyme Inhibition & Medicinal ChemistryISSN: 1475-6366Issue: 1Volume: 34
Authors: Serena Massari, Angela Corona, Simona Distinto, Jenny Desantis, Alessia Caredda, Stefano Sabatini, Giuseppe Manfroni, Tommaso Felicetti, Violetta Cecchetti, Christophe Pannecouque, et al.
Pages: 55 - 74Number of pages: 20 - Design and synthesis of a novel series of non-nucleoside HIV-1 inhibitors bearing pyrimidine and N-substituted aromatic piperazine(2018)Journal: Bioorganic & Medicinal Chemistry LettersISSN: 0960-894XIssue: 22Volume: 28
Authors: KaiJun Jin, YaLi Sang, Erik De Clercq, Christophe Pannecouque, Ge Meng
Pages: 3491 - 3495Number of pages: 5 - Design, synthesis, and antiviral evaluation of novel hydrazone-substituted thiophene[3,2-d]pyrimidine derivatives as potent human immunodeficiency virus-1 inhibitors(2018)Journal: Chemical Biology & Drug DesignISSN: 1747-0277Issue: 6Volume: 92
Authors: Zhao Wang, Dongwei Kang, Meng Chen, Gaochan Wu, Da Feng, Tong Zhao, Zhongxia Zhou, Zhipeng Huo, Lanlan Jing, Xiaofang Zuo, et al.
Pages: 2009 - 2021Number of pages: 13 - Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents(2018)Journal: Bioorganic & Medicinal Chemistry LettersISSN: 0960-894XIssue: 21Volume: 28
Authors: Konstantina Karypidou, Sergio Ribone, Mario A Quevedo, Leentje Persoons, Christophe Pannecouque, Christine Helsen, Frank Claessens, Wim Dehaen
Pages: 3472 - 3476Number of pages: 5 - Graphene Quantum Dots Based Systems As HIV Inhibitors(2018)Journal: Bioconjugate ChemistryISSN: 1043-1802Issue: 9Volume: 29
Authors: Daniela Iannazzo, Alessandro Pistone, Stefania Ferro, Laura De Luca, Anna Maria Monforte, Roberto Romeo, Maria Rosa Buemi, Christophe Pannecouque
Pages: 3084 - 3093Number of pages: 10 - Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d] pyrimidine non-nucleoside inhibitors(2018)Journal: eLifeVolume: 7
Authors: Yang Yang, Dongwei Kang, Laura A Nguyen, Zachary B Smithline, Christophe Pannecouque, Peng Zhan, Xinyong Liu, Thomas A Steitz
Number of pages: 20 - 5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase(2018)Journal: European Journal of Medicinal ChemistryISSN: 0223-5234Volume: 155
Authors: Lin Sun, Ping Gao, Guanyu Dong, Xujie Zhang, Xiqiang Cheng, Xiao Ding, Xueshun Wang, Dirk Daelemans, Erik De Clercq, Christophe Pannecouque, et al.
Pages: 714 - 724Number of pages: 11 - First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain(2018)Journal: Bioorganic & Medicinal Chemistry LettersISSN: 0960-894XIssue: 8Volume: 28
Authors: Boshi Huang, Xinhao Liu, Ye Tian, Dongwei Kang, Zhongxia Zhou, Dirk Daelemans, Erik De Clercq, Christophe Pannecouque, Peng Zhan, Xinyong Liu
Pages: 1348 - 1351 - The discovery of novel diarylpyri(mi)dine derivatives with high level activity against a wide variety of HIV-1 strains as well as against HIV-2(2018)Journal: Bioorganic & Medicinal ChemistryISSN: 0968-0896Issue: 8Volume: 26
Authors: Xueyi Lu, Jiapei Yang, Dongwei Kang, Ping Gao, Dirk Daelemans, Erik De Clercq, Christophe Pannecouque, Peng Zhan, Xinyong Liu
Pages: 2051 - 2060