Projects
From individual cancer genes to integrated cancer pathways in childhood cancer. KU Leuven
Evaluation of the quality of care of endometrial cancer in Belgium - EFFectiveness of Endometrial Cancer Treatment (EFFECT) project. KU Leuven
Cancer of the corpus uteri (uterine cancer) is the fourth most common cancer site in European women after breast, lung and colorectal cancer (From https://ecis.jrc.ec.europa.eu/, accessed on 05/09/2018). Every year around 1,500 new uterine cancer cases are diagnosed in Belgium. In comparison with other female cancers, such as breast or ovarian cancer, the evidence for the treatment of uterine cancer is rather limited. For instance, surgery is ...
Revealing the role of macrophage-associated immune-checkpoints in the sensing of apoptotic cancer cells to guide cancer chemoimmunotherapy KU Leuven
Therapeutic targeting of immune cell surface-tethered immune-checkpoints that inhibit anti-cancer immunity, via antibodies-based immune-checkpoint blockers (ICBs), has revolutionized the clinical oncological practice in recent years. Regrettably, only a subset of cancer patients tend to respond to these ICBs. Biomarker-guided, multimodal therapeutic regimen, are predicted to vastly improve the clinical efficacy of ICBs. Therein, one of the ...
Chair Fight against Cancer for Dr. Tine Vervoort:. Psychological dimensions of pain in the context of childhood cancer. Ghent University
In summary, the purpose of this chair (on the basis of a series of lectures at the Flemish Universities) 1) disseminating scientific knowledge about pain in children with pain is sketched from a biopsychosocial framework; 2) demonstrate the importance of pain research in the context of cancer (pediatric context) with particular attention will be paid to the importance of social context (eg, role of parents, doctors, nurses).; 3) a discussion ...
Damage-associated molecular patterns and immunogenic cancer cell death in cancer immunotherapy KU Leuven
Lipid profiling of cancer tissue: possibilities for cancer subtyming and applications for diagnosis and therapy. KU Leuven
Lung cancer is the deadliest of all cancers in the world. Particularly non-small cell lung cancer (NSCLC) is very prevalent and accounts for 80% of all lung cancer cases. One of the key problems in the management of NSCLC is the high failure rate of existing treatments, urging the need for new molecular biomarkers and novel therapeutic targets. So far, most efforts towards this molecular characterization have been carried out at the level of ...
Understanding the role of the WNT signaling pathway in breast cancer dormancy, therapy resistance and cancer relapse. KU Leuven
Breast cancer is the most common and most deadly neoplastic disease among women worldwide. Triple-negative breast cancer is a subtype of breast cancer characterized by the lack of expression of hormone and growth factor receptors, highly aggressive clinical features, poor prognosis, and high relapse rates. The lack of hormone and growth factor receptors renders targeted therapies that are highly efficient in other breast cancer subtypes ...