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Researcher
Johan Swinnen
- Disciplines:Oncology, Medical systems biology
Affiliations
- Laboratory of Lipid Metabolism and Cancer (Division)
Member
From1 Jan 2012 → Today - Laboratory of Lipid Metabolism and Cancer (Division)
Responsible
From1 Jan 2012 → Today
Projects
1 - 10 of 42
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: BOF - Concerted Research Project from 1994, BOF - projects
- Exploiting acquired vulnerabilities in fatty acid metabolism to overcome therapy resistance in castration resistant prostate cancerFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Exploitation of lipid metabolism in improving cancer immune checkpoint therapy responseFrom1 Jan 2021 → TodayFunding: FWO research project
- The role of Rer1 in ER-related homeostatic mechanismsFrom1 Jan 2021 → 31 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Lipometrix – towards an integrated lipidomics platform.From1 Nov 2020 → TodayFunding: BOF - research organisations
- Preclinical optimization of a novel combination approach exploiting a therapy-induced vulnerability to reactive oxygen species.From1 Sep 2019 → TodayFunding: Foundations, funds and other with scientific goal
- Association between different measures of global and local adiposity with clinico-pathological features, circulating markers, lipidomic profiles and outcome in postmenopausal breast cancer patients treated in the IBCSG 35-07 (SOLE) / BIG 1-07 trialFrom15 Jan 2019 → 14 Jan 2022Funding: Private funding of national origin - undefined
- Steering tumors towards a ferroptosis-mediated immunogenic death by exploiting vulnerabilities in lipid metabolismFrom1 Jan 2019 → TodayFunding: FWO research project
- Fatty acid metabolism as a novel adaptive response to high intratumoral pressure/temperature and promising target for the treatment of solid tumorsFrom1 Jan 2019 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
- A two-steps targeted radioactive iodine-based theragnostic strategy for small solid malignanciesFrom1 Oct 2018 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 101
- Unravelling Prostate Cancer Heterogeneity Using Spatial Approaches to Lipidomics and Transcriptomics(2022)
Authors: Xander Spotbeen, Johannes Swinnen
Number of pages: 16 - Heterogeneity of Synchronous Lung Metastasis Calls for Risk Stratification and Prognostic Classification: Evidence from a Population-Based Database(2022)
Authors: Shuncong Wang, Lei Chen, Johannes Swinnen, Yicheng Ni
Number of pages: 15 - The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes(2021)
Authors: Rita Derua, Johannes Swinnen
Number of pages: 15 - Too complex to fail? Targeting fatty acid metabolism for cancer therapy(2021)
Authors: Johannes Swinnen
Number of pages: 12 - Deciphering the Role of Extracellular Vesicles Derived from ZIKV-Infected hcMEC/D3 Cells on the Blood-Brain Barrier System(2021)
Authors: Antonios Fikatas, Jonas Dehairs, Johannes Swinnen, Christophe Pannecouque, Dominique Schols
Number of pages: 20 - Regulatory T cell differentiation is controlled by alpha KG-induced alterations in mitochondrial metabolism and lipid homeostasis(2021)
Authors: Ali Talebi, Jonas Dehairs, Johannes Swinnen
Number of pages: 30 - Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition(2021)
Authors: Xander Spotbeen, Jonas Dehairs, Rita Derua, Etienne Waelkens, Johannes Swinnen
Pages: 4981 - 4993Number of pages: 13 - New Insights on the PBMCs Phospholipidome in Obesity Demonstrate Modulations Associated with Insulin Resistance and Glycemic Status(2021)
Authors: Jonas Dehairs, Johannes Swinnen
Number of pages: 17 - Lipid metabolism in cancer: New perspectives and emerging mechanisms(2021)
Authors: Lindsay Broadfield, Ali Talebi, Johannes Swinnen, Sarah-Maria Fendt
Pages: 1363 - 1393Number of pages: 31 - BNIP3 promotes HIF-1 alpha-driven melanoma growth by curbing intracellular iron homeostasis(2021)
Authors: Mónica Vara Pérez, Matteo Rossi, Chris Van den Haute, Maria Livia Sassano, Abhishek Garg, Francesca Maria Bosisio, Jasper Wouters, Peter Vangheluwe, Willem Annaert, Johannes Swinnen, et al.
Number of pages: 22