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Researcher
Joris de Wit
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Cell signalling, Intracellular compartments and transport, Membrane structure and transport, Cognitive neuroscience, Developmental neuroscience, Neurological and neuromuscular diseases
- See also: De Wit Joris (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Synapse Biology (VIB-KU Leuven) (Lab)
Responsible
From1 Jan 2013 → Today - Laboratory of Synapse Biology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2017 → Today - de Wit Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Human Genetics (Department)
Member
From1 Jan 2013 → 31 Dec 2016
Projects
1 - 10 of 31
- Enhancer-AI: AI-driven modelling and design of cell type specific enhancers for gene therapyFrom1 Oct 2023 → TodayFunding: FWO Strategic Basic Research (SBO)
- Microglia-synapse molecular interactions in Alzheimer's diseaseFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Unravelling the regulatory code orchestrating neural circuit formationFrom5 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Resilience and vulnerability in the cellular phase of Alzheimer’s disease.From1 Oct 2021 → TodayFunding: BOF - Methusalem
- Development and Specification of Cortical Layer 1 MicrocircuitsFrom1 Sep 2021 → 22 Feb 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- Role of cell-surface receptor signaling mechanisms in dendritic spine maturation and plasticityFrom26 Aug 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Synapse type-specific multi-omics mapping of sensory experience-induced plasticityFrom1 Nov 2020 → 31 Dec 2022Funding: FWO junior postdoctoral fellowship
- Mapping of input-specific protein repertoires using state-of-the art genome engineering and imaging tools.From1 Oct 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mapping the synaptic proteome through site-specific protein biotinylationFrom1 Oct 2020 → 30 Sep 2023Funding: FWO senior postdoctoral fellowship
- Mapping the cell-surface molecule repertoires patterning hippocampal CA1 border interneuron connectivityFrom15 Sep 2020 → TodayFunding: FWO fellowships
Publications
31 - 40 of 46
- Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins (vol 95, pg 896, 2017)(2017)
Authors: Jonathan Elegheert, Vedrana Cvetkovska, Amber J Clayton, Christina Heroven, Kristel M Vennekens, Samuel N Smukowski, Michael C Regan, Wanyi Jia, Alexandra C Smith, Hiro Furukawa, et al.
Pages: 242 - 243 - Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins(2017)
Authors: Joris de Wit
Pages: 896 - 913 - Tau association with synaptic vesicles causes presynaptic dysfunction(2017)
Authors: Lujia Zhou, Joseph McInnes, Matthew Holt, Yu-Chun Wang, Sven Vilain, Bart De Strooper, Joris de Wit, Patrik Verstreken
Pages: 15295 - Neuronal Polarity: MAP2 Shifts Secretory Vesicles into High Gear for Long-Haul Transport down the Axon(2017)
Authors: Joris de Wit, Luís Filipe da Silva Ribeiro
Pages: 223 - 225 - Synapse biology in the 'circuit-age'-paths toward molecular connectomics(2017)
Authors: Joris de Wit
Pages: 102 - 110 - The sorting receptor SorCS1 controls axonal targeting of neurexin(2016)
Authors: Joris de Wit
- Specification of synaptic connectivity by cell surface interactions(2016)
Authors: Joris de Wit
Pages: 22 - 35 - Specification of synaptic connectivity by cell surface interactions(2016)
Authors: Joris de Wit, Anirvan Ghosh
Pages: 22 - 35 - The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors(2015)
Authors: Luís Filipe da Silva Ribeiro, Heather Rice, Joris de Wit
Pages: 764 - 780 - Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation(2015)
Authors: Vinoy Vijayan, Bart De Strooper, Joris de Wit, Patrik Verstreken
Pages: 1176 - 83
Patents
1 - 3 of 3