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Researcher
Joris de Wit
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Cell signalling, Intracellular compartments and transport, Membrane structure and transport, Cognitive neuroscience, Developmental neuroscience, Neurological and neuromuscular diseases
- See also: De Wit Joris (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Synapse Biology (VIB-KU Leuven) (Lab)
Responsible
From1 Jan 2013 → Today - Laboratory of Synapse Biology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2017 → Today - de Wit Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Human Genetics (Department)
Member
From1 Jan 2013 → 31 Dec 2016
Projects
1 - 10 of 31
- Enhancer-AI: AI-driven modelling and design of cell type specific enhancers for gene therapyFrom1 Oct 2023 → TodayFunding: FWO Strategic Basic Research (SBO)
- Microglia-synapse molecular interactions in Alzheimer's diseaseFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Unravelling the regulatory code orchestrating neural circuit formationFrom5 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Resilience and vulnerability in the cellular phase of Alzheimer’s disease.From1 Oct 2021 → TodayFunding: BOF - Methusalem
- Development and Specification of Cortical Layer 1 MicrocircuitsFrom1 Sep 2021 → 22 Feb 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- Role of cell-surface receptor signaling mechanisms in dendritic spine maturation and plasticityFrom26 Aug 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Synapse type-specific multi-omics mapping of sensory experience-induced plasticityFrom1 Nov 2020 → 31 Dec 2022Funding: FWO junior postdoctoral fellowship
- Mapping of input-specific protein repertoires using state-of-the art genome engineering and imaging tools.From1 Oct 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mapping the synaptic proteome through site-specific protein biotinylationFrom1 Oct 2020 → 30 Sep 2023Funding: FWO senior postdoctoral fellowship
- Mapping the cell-surface molecule repertoires patterning hippocampal CA1 border interneuron connectivityFrom15 Sep 2020 → TodayFunding: FWO fellowships
Publications
1 - 10 of 45
- Cell Adhesion Molecule Signaling at the Synapse: Beyond the Scaffold.(2024)
Authors: Ben Verpoort, Joris de Wit
Pages: a041501 - LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons(2023)
Authors: Sofie Beckers, Katerina Konstantoulea, Maarten Dewilde, Frederic Rousseau, Joost Schymkowitz, Tom Theys, Joris de Wit, Pierre Vanderhaeghen
- Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease(2023)
Authors: Nicky Thrupp, Mark Fiers, Joris de Wit, Kristofer Davie, Dietmar Thal, Bart De Strooper
Pages: 1021 - + - Proteomics-based synapse characterization: From proteins to circuits(2023)
Authors: Dan Dascenco, Joris de Wit
- Synaptrode: neural interface at the synapse level(2023)
Authors: Jasper Timmerman, Joris de Wit, Sebastian Haesler
Number of pages: 4 - KIF2A deficiency causes early-onset neurodegeneration(2022)
Authors: Joris de Wit
- MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior(2022)
Authors: Joris de Wit
- Hydrop enables droplet-based single-cell ATAC-seq and single-cell RNA-seq using dissolvable hydrogel beads(2022)
Authors: Florian De Rop, Jasper Janssens, Koen Theunis, Valerie Christiaens, Jasper Wouters, Gabriele Marcassa, Joris de Wit, Stein Aerts
- Role of regulatory C-terminal motifs in synaptic confinement of LRRTM2(2021)
Authors: Joris de Wit
Pages: 492 - 506 - Synaptic tau and synaptogyrin-3 are promising targets to tackle tauopathies.(2021)
Authors: Valerie Uytterhoeven, Joris de Wit, Bart De Strooper, Patrik Verstreken
Pages: e054187
Patents
1 - 3 of 3