Researcher
Gilles De Keulenaer
- Research Expertise:Force-length transducers for cardiovascular and pharmacological research (heartmuscle mechanics).
- Keywords:TRANSDUCER, BIOMECHANICS, CARDIAC MUSCLE, Pharmacy and pharmacology
- Disciplines:Biomechanics, Cardiac and vascular medicine, Physiology
- Research techniques:- Cardiac muscle mechanics - Echocardiography in small animals - Microsurgery in small animals for induction of heart failure - Basic molecular biology - Cell culture - Electrophysiology - Quantitative fluorometry
- Users of research expertise:- Other research groups - Research and product development departments in pharmaceutical companies
Affiliations
- Physiopharmacology (PHYSPHAR) (Research group)
Member
From1 Oct 2011 → Today - Physiology (Research group)
Responsible
From1 Oct 2003 → 30 Sep 2011
Projects
1 - 10 of 26
- Understanding the Effects of Heart Failure Treatments on Cancer Growth.From1 Nov 2023 → TodayFunding: FWO fellowships
- Small-Molecule ERBB4 Agonists to Treat Heart FailureFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Vevo LAZR-X Photoacoustic Imaging System;From1 Jun 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Cardiovascular disease and cancer are linked through the NRG1/ERBB3 signaling system.From26 Feb 2021 → 31 Dec 2021Funding: Other federal public and semi-governmental institutions
- Defining atrial myopathy in aging and disease (DIAMOND consortium).From1 Jan 2021 → TodayFunding: BOF - iBOF
- Studies of the ErbB4 receptor in myocardial non-myocytes to create new opportunities for the treatment of cardiac disease.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Neuregulin-1 as a therapy for atrial fibrillation and the role of the NRG-1/ErbB4 system in atrial remodelling.From1 Jan 2019 → 31 Dec 2022Funding: BOF - projects
- Maternale obesitas en "fetal programming": de gevolgen voor de voortplantingsfysiologie van de nakomelingen.From1 Oct 2018 → 30 Sep 2022Funding: BOF - Doctoral projects
- Identificatie van kleine moleculaire ErbB4 agonisten ter behandeling van cardiovasculaire ziekten.From1 Sep 2018 → 31 Aug 2022Funding: FWO research project (including WEAVE projects)
- Identification of small molecule ErbB4 agonist for treatment of heart failure, diabetic kidney injury and fibrotic disorders.From1 Jan 2018 → 31 Dec 2021Funding: IOF - Industrial Research Fund
Publications
1 - 10 of 79
- Activation of ErbB4 attenuates atrial fibrillation in mice(2024)
Authors: Gilles De Keulenaer, Guido De Meyer
Number of pages: 152 - Pathophysiology and clinical relevance of atrial myopathy(2024)
Authors: Michiel Tubeeckx, Gilles De Keulenaer, Hein Heidbuchel, Vincent Segers
Pages: 215 - 242 - Endothelial dysfunction at the cellular level in three dimensions(2023)
Authors: Vincent Segers, Gilles De Keulenaer
Pages: H398 - H413 - Cardiac electrophysiology studies in mice via the transjugular route(2022)
Authors: Kasper Favere, Griet Jacobs, Matthias Bosman, Johan De Sutter, Hielko Miljoen, Pieter-Jan Guns, Gilles De Keulenaer, Vincent Segers, Hein Heidbuchel
Pages: H763 - H773 - The identification of small-molecule ERBB4 agonists(2022)
Authors: Eline Feyen, Vincent Segers, Gilles De Keulenaer
Number of pages: 169 - ERBB4 and multiple microRNAs that target ERBB4 participate in pregnancy-related cardiomyopathy(2021)
Authors: Eline Feyen, Melanie Ricke-Hoch, Zarha Vermeulen, Michaela Scherr, Lindsey Dugaucquier, Janika Viereck, Tine Bruyns, Thomas Thum, Vincent Segers, Denise Hilfiker-Kleiner, et al.
Pages: 788 - 799 - Autocrine signaling in cardiac remodeling(2021)
Authors: Vincent Segers, Gilles De Keulenaer
- Sterile pericarditis in Aachener minipigs as a model for atrial myopathy and atrial fibrillation(2021)
Authors: Michiel Tubeeckx, Steven Laga, Christel Jacobs, Marina Stroe, Steven Van Cruchten, Bo Goovaerts, Hielko Miljoen, Guido De Meyer, Gilles De Keulenaer, Hein Heidbuchel, et al.
Pages: 1 - 14 - Neuregulin-1 compensates for endothelial nitric oxide synthase deficiency(2021)
Authors: Hadis Shakeri, Jente Boen, Sofie De Moudt, Jhana Hendrickx, Arthur Leloup, Griet Jacobs, Guido De Meyer, Gilles De Keulenaer, Pieter-Jan Guns, Vincent Segers
Pages: H2416 - H2428 - Ex vivo aortic stiffness in mice with different eNOS activity(2020)
Authors: Arthur Leloup, Cor Van Hove, Sofie De Moudt, Gilles De Keulenaer, Paul Fransen
Pages: 1233 - 1244
Patents
1 - 4 of 4