Researcher
Gilles De Keulenaer
- Research Expertise:Force-length transducers for cardiovascular and pharmacological research (heartmuscle mechanics).
- Keywords:TRANSDUCER, BIOMECHANICS, CARDIAC MUSCLE, Pharmacy and pharmacology
- Disciplines:Biomechanics, Cardiac and vascular medicine, Physiology
- Research techniques:- Cardiac muscle mechanics - Echocardiography in small animals - Microsurgery in small animals for induction of heart failure - Basic molecular biology - Cell culture - Electrophysiology - Quantitative fluorometry
- Users of research expertise:- Other research groups - Research and product development departments in pharmaceutical companies
Affiliations
- Physiopharmacology (PHYSPHAR) (Research group)
Member
From1 Oct 2011 → Today - Physiology (Research group)
Responsible
From1 Oct 2003 → 30 Sep 2011
Projects
1 - 10 of 26
- Understanding the Effects of Heart Failure Treatments on Cancer Growth.From1 Nov 2023 → TodayFunding: FWO fellowships
- Small-Molecule ERBB4 Agonists to Treat Heart FailureFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Vevo LAZR-X Photoacoustic Imaging System;From1 Jun 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Cardiovascular disease and cancer are linked through the NRG1/ERBB3 signaling system.From26 Feb 2021 → 31 Dec 2021Funding: Other federal public and semi-governmental institutions
- Defining atrial myopathy in aging and disease (DIAMOND consortium).From1 Jan 2021 → TodayFunding: BOF - iBOF
- Studies of the ErbB4 receptor in myocardial non-myocytes to create new opportunities for the treatment of cardiac disease.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Neuregulin-1 as a therapy for atrial fibrillation and the role of the NRG-1/ErbB4 system in atrial remodelling.From1 Jan 2019 → 31 Dec 2022Funding: BOF - projects
- Maternale obesitas en "fetal programming": de gevolgen voor de voortplantingsfysiologie van de nakomelingen.From1 Oct 2018 → 30 Sep 2022Funding: BOF - Doctoral projects
- Identificatie van kleine moleculaire ErbB4 agonisten ter behandeling van cardiovasculaire ziekten.From1 Sep 2018 → 31 Aug 2022Funding: FWO research project (including WEAVE projects)
- Identification of small molecule ErbB4 agonist for treatment of heart failure, diabetic kidney injury and fibrotic disorders.From1 Jan 2018 → 31 Dec 2021Funding: IOF - Industrial Research Fund
Publications
11 - 20 of 79
- The role of ErbB4 in cancer(2020)
Authors: Vincent Segers, Lindsey Dugaucquier, Eline Feyen, Hadis Shakeri, Gilles De Keulenaer
Pages: 1 - 18 - The role of endothelial miRNAs in myocardial biology and disease(2020)
Authors: Jente Boen, Andreas Gevaert, Gilles De Keulenaer, Emeline Van Craenenbroeck, Vincent Segers
Pages: 75 - 87 - Enhanced clinical phenotyping by mechanistic bioprofiling in heart failure with preserved ejection fraction: insights from the MEDIA-DHF study (The Metabolic Road to Diastolic Heart Failure)(2020)
Authors: Susan Stienen, Joao Pedro Ferreira, Masatake Kobayashi, Gregoire Preud'homme, Daniela Dobre, Jean-Loup Machu, Kevin Duarte, Emmanuel Bresso, Marie-Dominique Devignes, Natalia Lopez, et al.
Pages: 201 - 211 - Sex differences in circulating proteins in heart failure with preserved ejection fraction(2020)
Authors: Susan Stienen, Joao Pedro Ferreira, Masatake Kobayashi, Gregoire Preud'homme, Daniela Dobre, Jean-Loup Machu, Kevin Duarte, Emmanuel Bresso, Marie-Dominique Devignes, Natalia Lopez Andres, et al.
Pages: 1 - 14 - Role of non-myocyte NRG1/ERBB4 signaling in cardiac remodeling(2020)
Authors: Lindsey Dugaucquier, Vincent Segers, Gilles De Keulenaer
Number of pages: 188 - The role of endothelial autocrine NRG1/ERBB4 signaling in cardiac remodeling(2020)
Authors: Lindsey Dugaucquier, Eline Feyen, Ligia Monica Mateiu, Tine Anne Marie Bruyns, Gilles De Keulenaer, Vincent Segers
Pages: H443 - H455 - Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology(2019)
Authors: Rudolf A. de Boer, Gilles De Keulenaer, Johann Bauersachs, Dirk L. Brutsaert, John G. Cleland, Javier Diez, Xiao-Jun Du, Paul Ford, Frank R. Heinzel, Kenneth E. Lipson, et al.
Pages: 272 - 285 - Vascular smooth muscle cell contraction and relaxation in the isolated aorta(2019)
Authors: Arthur Leloup, Cor Van Hove, Sofie De Moudt, Guido De Meyer, Gilles De Keulenaer, Paul Fransen
- The continuous heart failure spectrum(2019)
Authors: Filippos Triposkiadis, Javed Butler, Francois M. Abboud, Paul W. Armstrong, Stamatis Adamopoulos, John J. Atherton, Johannes Backs, Johann Bauersachs, Daniel Burkhoff, Robert O. Bonow, et al.
Pages: 2155 - + - Cardiac endothelial cell transcriptome in neonatal, adult, and remodeling hearts(2019)
Authors: Zarha Vermeulen, Ligia Monica Mateiu, Lindsey Dugaucquier, Gilles De Keulenaer, Vincent Segers
Pages: 186 - 196
Patents
1 - 4 of 4