Researcher
Gilles De Keulenaer
- Research Expertise:Force-length transducers for cardiovascular and pharmacological research (heartmuscle mechanics).
- Keywords:TRANSDUCER, BIOMECHANICS, CARDIAC MUSCLE, Pharmacy and pharmacology
- Disciplines:Biomechanics, Cardiac and vascular medicine, Physiology
- Research techniques:- Cardiac muscle mechanics - Echocardiography in small animals - Microsurgery in small animals for induction of heart failure - Basic molecular biology - Cell culture - Electrophysiology - Quantitative fluorometry
- Users of research expertise:- Other research groups - Research and product development departments in pharmaceutical companies
Affiliations
- Physiopharmacology (PHYSPHAR) (Research group)
Member
From1 Oct 2011 → Today - Physiology (Research group)
Responsible
From1 Oct 2003 → 30 Sep 2011
Projects
1 - 10 of 26
- Understanding the Effects of Heart Failure Treatments on Cancer Growth.From1 Nov 2023 → TodayFunding: FWO fellowships
- Small-Molecule ERBB4 Agonists to Treat Heart FailureFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Vevo LAZR-X Photoacoustic Imaging System;From1 Jun 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Cardiovascular disease and cancer are linked through the NRG1/ERBB3 signaling system.From26 Feb 2021 → 31 Dec 2021Funding: Other federal public and semi-governmental institutions
- Defining atrial myopathy in aging and disease (DIAMOND consortium).From1 Jan 2021 → TodayFunding: BOF - iBOF
- Studies of the ErbB4 receptor in myocardial non-myocytes to create new opportunities for the treatment of cardiac disease.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Neuregulin-1 as a therapy for atrial fibrillation and the role of the NRG-1/ErbB4 system in atrial remodelling.From1 Jan 2019 → 31 Dec 2022Funding: BOF - projects
- Maternale obesitas en "fetal programming": de gevolgen voor de voortplantingsfysiologie van de nakomelingen.From1 Oct 2018 → 30 Sep 2022Funding: BOF - Doctoral projects
- Identificatie van kleine moleculaire ErbB4 agonisten ter behandeling van cardiovasculaire ziekten.From1 Sep 2018 → 31 Aug 2022Funding: FWO research project (including WEAVE projects)
- Identification of small molecule ErbB4 agonist for treatment of heart failure, diabetic kidney injury and fibrotic disorders.From1 Jan 2018 → 31 Dec 2021Funding: IOF - Industrial Research Fund
Publications
41 - 50 of 79
- ErbB2 signaling at the crossing between heart failure and cancer(2016)
Authors: Zarha Vermeulen, Vincent Segers, Gilles De Keulenaer
- Elastin fragmentation in atherosclerotic mice leads to intraplaque neovascularization, plaque rupture, myocardial infarction, stroke, and sudden death(2015)
Authors: Carole Van der Donckt, Jozef L. Van Herck, Dorien Schrijvers, Greetje Vanhoutte, Marleen Verhoye, Ines Blockx, Dries Bauters, Henri R. Lijnen, Judith C. Sluimer, Lynn Roth, et al.
Pages: 1049 - 1058A - Letter by Brutsaert and De Keulenaer regarding article(2015)
Authors: Dirk L. Brutsaert, Gilles De Keulenaer
Pages: 839 - 839 - Neuregulin-1 improves right ventricular function and attenuates monocrotaline-induced pulmonary arterial hypertension(2015)
Authors: P. Mendes-Ferreira, C. Maia-Rocha, R. Adao, Gilles De Keulenaer, et al.
Pages: 1 - 15 - Chronic intermittent mental stress promotes atherosclerotic plaque vulnerability, myocardial infarction and sudden death in mice(2015)
Authors: Lynn Roth, Miche Rombouts, Dorien Schrijvers, Katrien Lemmens, Gilles De Keulenaer, Wim Martinet, Guido De Meyer
Pages: 288 - 294 - Cardiac endothelium-myocyte interaction(2015)
Authors: Shir Lynn Lim, Carolyn S.P. Lam, Vincent Segers, Dirk L. Brutsaert, Gilles De Keulenaer
Pages: 2050 - + - Applanation tonometry in mice a novel noninvasive technique to assess pulse wave velocity and arterial stiffness(2014)
Authors: Arthur Leloup, Paul Fransen, Cor Van Hove, Marc Demolder, Gilles De Keulenaer, Dorien Schrijvers
Pages: 195 - 200 - Left ventricular diastolic dysfunction and myocardial stiffness in diabetic mice is attenuated by inhibition of dipeptidyl peptidase 4(2014)
Authors: Nazha Hamdani, Anne-Sophie Hervent, Leni Vandekerckhove, Veerle Matheeussen, Marc Demolder, Lesley Baerts, Ingrid De Meester, Wolfgang A. Linke, Walter J. Paulus, Gilles De Keulenaer
Pages: 423 - 431 - Is overemphasizing diastolic dysfunction in heart failure with a preserved ejection fraction too narrow minded?(2014)
Authors: Gilles De Keulenaer
Pages: 107 - 109 - Therapeutic potential of neuregulin-1 in cardiovascular disease(2013)
Authors: Pedro Mendes-Ferreira, Gilles De Keulenaer, Adelino F. Leite-Moreira, Carmen Bras-Silva
Pages: 836 - 842
Patents
1 - 4 of 4