Researcher
Charlotte Scott
- Keywords (Ghent University):inflammation, Liver, Dendritic cells, Macrophages, intestine
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Immunogenetics, Inflammation, Innate immunity, Gastro-enterology, Hepatology
- See also: Charlotte Scott (Flanders Institute for Biotechnology)
Affiliations
- Scott Lab (Research group)
Responsible
From1 Jan 2020 → Today - Guilliams Lab (Research group)
Responsible
From1 Oct 2019 → 31 Dec 2019 - Guilliams Lab (Research group)
Member
From1 Jul 2017 → 30 Sep 2019 - Lambrecht and Hammad Lab (Research group)
Member
From1 Jan 2017 → 30 Jun 2017 - Department of Biomedical molecular biology (Department)
Member
From1 May 2015 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2013 → 30 Apr 2015
Projects
1 - 10 of 20
- Investigating a potential protective role for Kupffer cells (KCs) in obesity-induced hepatocellular carcinoma (ProteKCt)From1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Unraveling how ZEB1 expression in conventional type I dendritic cells regulates the presence of other cell types specifically in the spleen and the functional consequences of this regulation.From1 Nov 2023 → TodayFunding: FWO fellowships
- Obesity-associated Hepatocellular Carcinoma at Single Cell Resolution for Risk Prediction and Novel Therapeutics - HepatoSCRIPTFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Investigating how chronic fibrosis in the liver alters hepatic macrophage responses to systemic infections.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Understanding the roles of distinct Kupffer cell activation states in acetaminophen-induced acute liver injury.From1 Oct 2022 → TodayFunding: BOF - postdoctoral mandates
- Unravelling the cell-cell circuits underlying the tissue memory of non-alcoholic fatty liver diseaseFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Investigating the role of Kupffer Cells in driving the progression from NAFLD to Hepatocellular CarcinomaFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
11 - 20 of 70
- Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches(2022)
Authors: Martin Guilliams, Johnny Bonnardel, Birthe Haest, Bart Vanderborght, Camille Wagner, Anneleen Remmerie, Anna Bujko, Liesbet Martens, Tinne Thoné, Federico Francesco De Ponti, et al.
Pages: 379 - 396 - Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues(2022)
Authors: Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Daliya Kancheva, Jonathan Bastos, Monica Vara-Perez, Ana Rita Pombo Antunes, Liesbet Martens, Charlotte Scott, Jo Van Ginderachter, et al.
Pages: 2354 - 2388 - Who on IRF are you? IRF8 deficiency redirects cDC1 lineage commitment(2022)
Authors: Kathryn Waller, Charlotte Scott
Pages: 687 - 689 - Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors(2022)
Authors: Noah Bonine, Tinne Thoné, Bavo Vanneste, Charlotte Scott
Number of pages: 1 - In matters of the heart, (cellular) communication is key(2021)
Authors: Federico Francesco De Ponti, Charlotte Scott
Pages: 1906 - 1908 - The conventional dendritic cell lineage is born(2021)
Authors: Martin Guilliams, Charlotte Scott
Pages: 623 - 623 - ILC3s control splenic cDC homeostasis via lymphotoxin signaling(2021)
Authors: Matthias Vanderkerken, Antonio Pires da Silva Baptista, Marco De Giovanni, Satoshi Fukuyama, Charlotte Scott, Paula S. Norris, Gerard Eberl, James P. Di Santo, Eric Vivier, Yvan Saeys, et al.
- Welcoming c-MAF to the macrophage transcription factor VAM-ily(2021)
Authors: Pieter Louwe, Charlotte Scott
- A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism(2021)
Authors: Leen Catrysse, Bastiaan Maes, Parul Mehrotra, Arne Martens, Esther Hoste, Liesbet Martens, Christian Maueröder, Anneleen Remmerie, Anna Bujko, Karolina Slowicka, et al.
- Hepatic macrophage responses in inflammation, a function of plasticity, heterogeneity or both?(2021)
Authors: Christian Zwicker, Anna Bujko, Charlotte Scott