Researcher
Charlotte Scott
- Keywords (Ghent University):inflammation, Liver, Dendritic cells, Macrophages, intestine
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Immunogenetics, Inflammation, Innate immunity, Gastro-enterology, Hepatology
- See also: Charlotte Scott (Flanders Institute for Biotechnology)
Affiliations
- Scott Lab (Research group)
Responsible
From1 Jan 2020 → Today - Guilliams Lab (Research group)
Responsible
From1 Oct 2019 → 31 Dec 2019 - Guilliams Lab (Research group)
Member
From1 Jul 2017 → 30 Sep 2019 - Lambrecht and Hammad Lab (Research group)
Member
From1 Jan 2017 → 30 Jun 2017 - Department of Biomedical molecular biology (Department)
Member
From1 May 2015 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2013 → 30 Apr 2015
Projects
1 - 10 of 20
- Investigating a potential protective role for Kupffer cells (KCs) in obesity-induced hepatocellular carcinoma (ProteKCt)From1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Unraveling how ZEB1 expression in conventional type I dendritic cells regulates the presence of other cell types specifically in the spleen and the functional consequences of this regulation.From1 Nov 2023 → TodayFunding: FWO fellowships
- Obesity-associated Hepatocellular Carcinoma at Single Cell Resolution for Risk Prediction and Novel Therapeutics - HepatoSCRIPTFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Investigating how chronic fibrosis in the liver alters hepatic macrophage responses to systemic infections.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Understanding the roles of distinct Kupffer cell activation states in acetaminophen-induced acute liver injury.From1 Oct 2022 → TodayFunding: BOF - postdoctoral mandates
- Unravelling the cell-cell circuits underlying the tissue memory of non-alcoholic fatty liver diseaseFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Investigating the role of Kupffer Cells in driving the progression from NAFLD to Hepatocellular CarcinomaFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
31 - 40 of 70
- ZEBs : novel players in immune cell development and function(2019)
Authors: Charlotte Scott, Kyla D Omilusik
Pages: 431 - 446 - A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment(2019)
Authors: Hannah Van Hove, Liesbet Martens, Isabelle Scheyltjens, Karen De Vlaminck, Ana Rita Pombo Antunes, Sofie De Prijck, Niels Vandamme, Sebastiaan De Schepper, Gert Van Isterdael, Charlotte Scott, et al.
Pages: 1021 - 1035 - Stellate cells, hepatocytes, and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche(2019)
Authors: Johnny Bonnardel, Wouter T'Jonck, Djoere Gaublomme, Robin Browaeys, Charlotte Scott, Liesbet Martens, Bavo Vanneste, Sofie De Prijck, Sergei A Nedospasov, Anna Kremer, et al.
Pages: 638 - 654 - The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages(2018)
Authors: Charlotte Scott, Wouter T'Jonck, Liesbet Martens, Helena Todorov, Dorine Sichien, Bieke Soen, Johnny Bonnardel, Sofie De Prijck, Niels Vandamme, Wouter Saelens, et al.
Pages: 312 - 325 - 'NOTCHing up' the in vitro production of dendritic cells(2018)
Authors: Martin Guilliams, Charlotte Scott
Pages: 765 - 767 - Macrophages and lipid metabolism(2018)
Authors: Anneleen Remmerie, Charlotte Scott
Pages: 27 - 42 - The role of Kupffer cells in hepatic iron and lipid metabolism(2018)
Authors: Charlotte Scott, Martin Guilliams
Pages: 1197 - 1199 - Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens(2018)
Authors: Sylvain Normand, Nadine Waldschmitt, Andreas Neerincx, Ruben Julio Martinez-Torres, Camille Chauvin, Aurelie Couturier-Maillard, Olivier Boulard, Laetitia Cobret, Fawaz Awad, Ludovic Huot, et al.
- Tissue unit-ed : lung cells team up to drive alveolar macrophage development(2018)
Authors: Charlotte Scott, Martin Guilliams
Pages: 898 - 900 - Myocarditis elicits dendritic cell and monocyte infiltration in the heart and self-antigen presentation by conventional type 2 dendritic cells(2018)
Authors: Katrien Van Der Borght, Charlotte Scott, Liesbet Martens, Dorine Sichien, Gert Van Isterdael, Veronika Nindl, Yvan Saeys, Louis Boon, Burkhard Ludewig, Thierry Gillebert, et al.