Researcher
Charlotte Scott
- Keywords (Ghent University):inflammation, Liver, Dendritic cells, Macrophages, intestine
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Immunogenetics, Inflammation, Innate immunity, Gastro-enterology, Hepatology
- See also: Charlotte Scott (Flanders Institute for Biotechnology)
Affiliations
- Scott Lab (Research group)
Responsible
From1 Jan 2020 → Today - Guilliams Lab (Research group)
Responsible
From1 Oct 2019 → 31 Dec 2019 - Guilliams Lab (Research group)
Member
From1 Jul 2017 → 30 Sep 2019 - Lambrecht and Hammad Lab (Research group)
Member
From1 Jan 2017 → 30 Jun 2017 - Department of Biomedical molecular biology (Department)
Member
From1 May 2015 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2013 → 30 Apr 2015
Projects
1 - 10 of 20
- Investigating a potential protective role for Kupffer cells (KCs) in obesity-induced hepatocellular carcinoma (ProteKCt)From1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Unraveling how ZEB1 expression in conventional type I dendritic cells regulates the presence of other cell types specifically in the spleen and the functional consequences of this regulation.From1 Nov 2023 → TodayFunding: FWO fellowships
- Obesity-associated Hepatocellular Carcinoma at Single Cell Resolution for Risk Prediction and Novel Therapeutics - HepatoSCRIPTFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Investigating how chronic fibrosis in the liver alters hepatic macrophage responses to systemic infections.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Understanding the roles of distinct Kupffer cell activation states in acetaminophen-induced acute liver injury.From1 Oct 2022 → TodayFunding: BOF - postdoctoral mandates
- Unravelling the cell-cell circuits underlying the tissue memory of non-alcoholic fatty liver diseaseFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Investigating the role of Kupffer Cells in driving the progression from NAFLD to Hepatocellular CarcinomaFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
1 - 10 of 70
- Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis(2024)
Authors: Kevin De Muynck, Lander Heyerick, Federico Francesco De Ponti, Bart Vanderborght, Tim Meese, Sanne Van Campenhout, Leen Baudonck, Eva Gijbels, Pedro M. Rodrigues, Jesus M. Banales, et al.
Pages: 269 - 288 - Studying macrophages in the murine steatotic liver using flow cytometry and confocal microscopy(2023)Series: Methods in molecular biology
Authors: Zhuangzhuang Liu, Pieter Louwe, Charlotte Scott, Elvira Mass
Pages: 207 - 230 - Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis(2023)
Authors: Kevin De Muynck, Bart Vanderborght, Federico Francesco De Ponti, Eva Gijbels, Sophie Van Welden, Martin Guilliams, Charlotte Scott, Alain Beschin, Mathieu Vinken, Sander Lefere, et al.
Pages: 366 - 379 - A20 is a master switch of IL-33 signalling in macrophages and determines IL-33-induced lung immunity(2023)
Authors: Aurora Holgado Muñoz, Zhuangzhuang Liu, Aigerim Aidarova, Christina Müller, Mira Haegman, Yasmine Driege, Marja Kreike, Charlotte Scott, Inna Afonina, Rudi Beyaert
Pages: 244 - 256.e4 - Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma(2023)
Authors: Bart Vanderborght, Kevin De Muynck, Eva Gijbels, Sander Lefere, Charlotte Scott, Martin Guilliams, Alain Beschin, Mathieu Vinken, Xavier Verhelst, Anja Geerts, et al.
Pages: 2615 - 2628 - Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes(2023)
Authors: Anastasiia Gainullina, Denis A. Mogilenko, Li-Hao Huang, Helena Todorov, Vipin Narang, Ki-Wook Kim, Lim Sheau Yng, Andrew Kent, Baosen Jia, Kumba Seddu, et al.
- Modulating hepatic macrophages with annexin A1 in non-alcoholic steatohepatitis(2022)
Authors: Federico Francesco De Ponti, Charlotte Scott
Pages: 1111 - 1115 - A breath of fresh macrophages ameliorates inflammation in the hypoxic lung(2022)
Authors: Federico Francesco De Ponti, Charlotte Scott
Pages: 820 - 822 - Liver macrophages in health and disease(2022)
Authors: Martin Guilliams, Charlotte Scott
Pages: 1515 - 1529 - Complementarity of single-nucleus and single-cell RNA sequencing to study the transcriptional heterogeneity of neuroblastoma tumors(2022)
Authors: Noah Bonine, Tinne Thoné, Bavo Vanneste, Charlotte Scott
Number of pages: 1