Researcher
Charlotte Scott
- Keywords (Ghent University):inflammation, Liver, Dendritic cells, Macrophages, intestine
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Immunogenetics, Inflammation, Innate immunity, Gastro-enterology, Hepatology
- See also: Charlotte Scott (Flanders Institute for Biotechnology)
Affiliations
- Scott Lab (Research group)
Responsible
From1 Jan 2020 → Today - Guilliams Lab (Research group)
Responsible
From1 Oct 2019 → 31 Dec 2019 - Guilliams Lab (Research group)
Member
From1 Jul 2017 → 30 Sep 2019 - Lambrecht and Hammad Lab (Research group)
Member
From1 Jan 2017 → 30 Jun 2017 - Department of Biomedical molecular biology (Department)
Member
From1 May 2015 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2013 → 30 Apr 2015
Projects
1 - 10 of 20
- Investigating a potential protective role for Kupffer cells (KCs) in obesity-induced hepatocellular carcinoma (ProteKCt)From1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Unraveling how ZEB1 expression in conventional type I dendritic cells regulates the presence of other cell types specifically in the spleen and the functional consequences of this regulation.From1 Nov 2023 → TodayFunding: FWO fellowships
- Obesity-associated Hepatocellular Carcinoma at Single Cell Resolution for Risk Prediction and Novel Therapeutics - HepatoSCRIPTFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Investigating how chronic fibrosis in the liver alters hepatic macrophage responses to systemic infections.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Understanding the roles of distinct Kupffer cell activation states in acetaminophen-induced acute liver injury.From1 Oct 2022 → TodayFunding: BOF - postdoctoral mandates
- Unravelling the cell-cell circuits underlying the tissue memory of non-alcoholic fatty liver diseaseFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Investigating the role of Kupffer Cells in driving the progression from NAFLD to Hepatocellular CarcinomaFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
41 - 50 of 70
- A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation(2018)
Authors: Sofie Voet, Conor Mc Guire, Nora Hagemeyer, Arne Martens, Anna Schroeder, Peter Wieghofer, Carmen Daems, Ori Staszewski, Marta Joana Costa Jordao, Mozes Sze, et al.
- Development of conventional dendritic cells : from common bone marrow progenitors to multiple subsets in peripheral tissues(2017)
Authors: Dorine Sichien, Martin Guilliams, Charlotte Scott
Pages: 831 - 844 - TGFβR signalling controls CD103⁺CD11b⁺ dendritic cell development in the intestine(2017)
Authors: CC Bain, J Montgomery, Charlotte Scott, JM Kel, MJH Girard-Madoux, Liesbet Martens, TFP Zangerle-Murray, J Ober-Blobaum, D Lindenbergh-Kortleve, JN Samsom, et al.
- Kupffer cell pool is maintained by local proliferation and the differentiation of bone marrow monocytes into short-lived monocyte-derived Kupffer cells during non-alcoholic steatohepatitis and recovery(2017)Volume: 66
Authors: Charlotte Scott, Sander Lefere, Sarah Raevens, Eliene Bogaerts, Annelies Paridaens, Anja Geerts, Martin Guilliams
Pages: S435 - S435 - Isolation and identification of intestinal myeloid cells(2017)Series: Methods in Molecular Biology
Authors: Charlotte Scott, Calum C Bain, Allan McI Mowat, Björn E Clausen, Jon D Laman
Pages: 223 - 239 - Myocardial infarction primes autoreactive T cells through activation of dendritic cells(2017)
Authors: Katrien Van Der Borght, Charlotte Scott, Veronika Nindl, Ann Bouché, Liesbet Martens, Dorine Sichien, Justine Van Moorleghem, Manon Vanheerswynghels, Sofie De Prijck, Yvan Saeys, et al.
Pages: 3005 - 3017 - Barrier-tissue macrophages : functional adaptation to environmental challenges(2017)
Authors: Allan Mcl Mowat, Charlotte Scott, Calum C Bain
Pages: 1258 - 1270 - Does niche competition determine the origin of tissue-resident macrophages?(2017)
Authors: Martin Guilliams, Charlotte Scott
Pages: 451 - 460 - Non-alcoholic steatohepatitis induces transient changes within the liver macrophage pool(2017)
Authors: Charlotte Scott, Sander Lefere, Sarah Raevens, Eliene Bogaerts, Annelies Paridaens, Anja Geerts, Martin Guilliams
Pages: 74 - 83 - IRF8 transcription factor controls survival and function of terminally differentiated conventional and plasmacytoid dendritic cells, respectively(2016)
Authors: Dorine Sichien, Charlotte Scott, Liesbet Martens, Matthias Vanderkerken, Sofie Van Gassen, Maud Plantinga, Thorsten Joeris, Sofie De Prijck, Leen Vanhoutte, Manon Vanheerswynghels, et al.
Pages: 626 - 640