Researcher
Charlotte Scott
- Keywords (Ghent University):inflammation, Liver, Dendritic cells, Macrophages, intestine
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Immunogenetics, Inflammation, Innate immunity, Gastro-enterology, Hepatology
- See also: Charlotte Scott (Flanders Institute for Biotechnology)
Affiliations
- Scott Lab (Research group)
Responsible
From1 Jan 2020 → Today - Guilliams Lab (Research group)
Responsible
From1 Oct 2019 → 31 Dec 2019 - Guilliams Lab (Research group)
Member
From1 Jul 2017 → 30 Sep 2019 - Lambrecht and Hammad Lab (Research group)
Member
From1 Jan 2017 → 30 Jun 2017 - Department of Biomedical molecular biology (Department)
Member
From1 May 2015 → Today - Department of Internal medicine (Department)
Member
From1 Oct 2013 → 30 Apr 2015
Projects
1 - 10 of 20
- Investigating a potential protective role for Kupffer cells (KCs) in obesity-induced hepatocellular carcinoma (ProteKCt)From1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Unraveling how ZEB1 expression in conventional type I dendritic cells regulates the presence of other cell types specifically in the spleen and the functional consequences of this regulation.From1 Nov 2023 → TodayFunding: FWO fellowships
- Obesity-associated Hepatocellular Carcinoma at Single Cell Resolution for Risk Prediction and Novel Therapeutics - HepatoSCRIPTFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Investigating how chronic fibrosis in the liver alters hepatic macrophage responses to systemic infections.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Understanding the roles of distinct Kupffer cell activation states in acetaminophen-induced acute liver injury.From1 Oct 2022 → TodayFunding: BOF - postdoctoral mandates
- Unravelling the cell-cell circuits underlying the tissue memory of non-alcoholic fatty liver diseaseFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Investigating the role of Kupffer Cells in driving the progression from NAFLD to Hepatocellular CarcinomaFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
21 - 30 of 70
- Macrophage subsets in obesity, aligning the liver and adipose tissue(2020)
Authors: Anneleen Remmerie, Liesbet Martens, Charlotte Scott
- Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver(2020)
Authors: Anneleen Remmerie, Liesbet Martens, Tinne Thoné, Angela Castoldi, Ruth Seurinck, Benjamin Pavie, Joris Roels, Bavo Vanneste, Sofie De Prijck, Mathias Vanhockerhout, et al.
Pages: 641 - 657.e1–e14 - Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection(2020)
Authors: Cédric Bosteels, Katrijn Neyt, Manon Vanheerswynghels, Mary van Helden, Dorine Sichien, Sofie De Prijck, Victor Bosteels, Niels Vandamme, Liesbet Martens, Yvan Saeys, et al.
Pages: 1039 - 1056 - Deep learning of immune cell differentiation(2020)
Authors: Alexandra Maslova, Ricardo N. Ramirez, Ke Ma, Hugo Schmutz, Chendi Wang, Curtis Fox, Bernard Ng, Christophe Benoist, Sara Mostafavi, Charlotte Scott, et al.
Pages: 25655 - 25666 - ImmGen at 15(2020)
Authors: Stephanie Vargas Aguilar, Oscar Aguilar, Rhys Allan, El Ad David Amir, Veronique Angeli, Maxim N. Artyomov, Natasha Asinovski, Jilian Astarita, K. Frank Austen, Geetika Bajpai, et al.
Pages: 700 - 703 - Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis(2020)
Authors: Lise Van Wyngene, Tineke Vanderhaeghen, Steven Timmermans, Jolien Vandewalle, Kelly Van Looveren, Jolien Souffriau, Charlotte Wallaeys, Melanie Eggermont, Sam Ernst, Evelien Van Hamme, et al.
- Transcriptional regulation of DC fate specification(2020)
Authors: Cédric Bosteels, Charlotte Scott
Pages: 38 - 46 - Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury(2020)
Authors: Elke Ydens, Lukas Amann, Bob Asselbergh, Charlotte Scott, Liesbet Martens, Dorine Sichien, Omar Mossad, Thomas Blank, Sofie De Prijck, Donovan Low, et al.
Pages: 676 - 689 - OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis(2020)
Authors: Lien Verboom, Arne Martens, Dario Priem, Esther Hoste, Mozes Sze, Hanna-Kaisa Vikkula, Lisette Van Hove, Sofie Voet, Jonathan Maelfait, Laura Bongiovanni, et al.
Pages: 2237 - 2247 - Priority lane to cDC1 open for IRF8⁺ progenitors(2019)
Authors: Martin Guilliams, Charlotte Scott
Pages: 1795 - 1797