Organisation
Laboratory of Computational Biology (VIB-KU Leuven)
Division
Research in the Laboratory of Computational Biology is focusing on gene and genome regulation, with applications in Drosophila and cancer, and on integrative genomics, developing computational methods for genomic data integration and analysis of next-generation sequence data.
Current researchers
11 - 20 of 21 results
- Eren Can Eksi (Member)
- Nikolai Hecker (Member)
- Jasper Janssens (Member)
- Niklas Kempynck (Member)
- Vasilis Konstantakos (Member)
- David Mauduit (Member)
- Alexandra Pančíková (Member)
- Gabriele Partel (Member)
- Olga Sigalova (Member)
- Ibrahim Ihsan Taskiran (Member)
Projects
11 - 20 of 64
- A whole-organism approach to uncover gene regulatory mechanisms in Drosophila melanogaster: towards a regulatory map at single-cell resolutionFrom1 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mapping gene regulatory networks in the era of single-cell multi-omicsFrom1 Sep 2022 → TodayFunding: BOF - doctoral mandates
- Modeling gene regulation through end-to-end deep learning for expression predictionFrom1 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Integration of long read genome sequencing and single-cell multi-omics to identify genetic variation underlying Parkinson’s diseaseFrom1 Sep 2022 → TodayFunding: BOF - doctoral mandates
- Rebus EsperFrom29 Jun 2022 → TodayFunding: Other federal scientific institutions
- Advanced infrastructure for fabrication of next-generation micro- and nanosystemsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Cell-cell cOmmuNicaTion As a driver of Cancer cell state identiTy - Decoding the impact of cell-cell communications on the identity of tumor states in skin cancersFrom1 Jan 2022 → TodayFunding: FWO EOS
- Unravelling the regulatory code orchestrating neural circuit formationFrom5 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Deciphering the evolution of gene regulatory networks and enhancer architectures in neuronal cell types using single-cell deep learning and comparative genomicsFrom1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- OncoAI - a machine-learning framework to predict cancer cell vulnerability at the gene-regulatory levelFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 177
- Mass Spectrometry of Flame Figures(2015)
Authors: Jasper Wouters, Etienne Waelkens, Siegfried Segaert, Joost van den Oord
Pages: 734 - 735 - First-in-Human Proof-of-Concept Study: Intralesional Administration of BQ788, an Endothelin Receptor B Antagonist, to Melanoma Skin Metastases(2015)
Authors: Jasper Wouters, Joost van den Oord
Pages: 1121 - 1122 - Prognostic and predictive biomarkers in melanoma: an update(2016)
Authors: Jasper Wouters
Pages: 223 - 237 - Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche(2016)
Authors: Olivier Govaere, Jasper Wouters, An Ceulemans, Frederik Nevens, Baki Topal, Hugo Vankelecom, Tania Roskams
Pages: 609 - 17 - KERATIN 19: A KEY ROLE PLAYER IN THE INVASION OF HUMAN HEPATOCELLULAR CARCINOMAS(2013)
Authors: Olivier Govaere, MIna Komuta, Joost Berkers, B Spee, Carl Janssen, F de Luca, A Katoonizadeh, Jasper Wouters, LC van Kempen, A Durnez, et al.
Pages: S430 - S430 - Keratin 19: a key role player in the invasion of human hepatocellular carcinomas(2014)
Authors: Olivier Govaere, MIna Komuta, Joost Berkers, Bart Spee, Carl Janssen, Francesca de Luca, Aezam Katoonizadeh, Jasper Wouters, Léon C van Kempen, Anne Durnez, et al.
Pages: 674 - 685 - Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes(2013)
Authors: Hugo Vankelecom, Wouter Van Delm, Jasper Wouters, Olivier Govaere, Tania Roskams, Baki Topal
- Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease(2022)
Authors: Olivier Govaere, Jasper Wouters, Matthias Van Haele, Baki Topal, Tania Roskams
Pages: 1001 - 1012 - A novel hypoxia-associated subset of FN1(high)MITF(low) melanoma cells: identification, characterization, and prognostic value(2014)
Authors: Jasper Wouters, Marguerite Stas, Olivier Govaere, Kathleen Barrette, Hugo Vankelecom, Joost van den Oord
Pages: 1088 - 1100 - Vision-related convergent gene losses reveal SERPINE3's unknown role in the eye(2022)
Authors: Nikolai Hecker