Organisation
Laboratory of Computational Biology (VIB-KU Leuven)
Division
Research in the Laboratory of Computational Biology is focusing on gene and genome regulation, with applications in Drosophila and cancer, and on integrative genomics, developing computational methods for genomic data integration and analysis of next-generation sequence data.
Current researchers
21 - 21 of 21 results
- Roel Vandepoel (Member)
Projects
21 - 30 of 64
- Resolving the gene-regulatory dimension of the Fly Cell Atlas using single-cell multi-omics and deep learningFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- EU-Genomics: EU Infrastructure for Genome AnalysisFrom1 Jan 2021 → TodayFunding: FWO Large scale research infrastructure
- Charting non-small cell lung cancer evolution and heterogeneity through multi-omics analysis and deconvolutionFrom1 Oct 2020 → 1 Jul 2022Funding: FWO senior postdoctoral fellowship
- How to switch on a complex brain: single-cell technologies to connect emergent nervous system activity with neural cell specification.From1 Oct 2020 → TodayFunding: BOF - projects
- Deciphering enhancer logic of cell fate decisions during human neural tube and neural crest development, using single-cell multi-omics and machine learning.From8 Jul 2020 → TodayFunding: FWO fellowships
- Translational research-oriented technology platform for single cell analysisFrom1 May 2020 → TodayFunding: BOF - scientific equipment program
- FemtoFac: Femtosecond pulse laser Facility for micro & nanoscale research.From1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- High-troughput mapping of melanoma cell states and transitions using pooled CRISPR screening with single-cell readoutFrom1 Oct 2019 → 18 Mar 2022Funding: Foundations, funds and other with scientific goal
- Development of an interdisciplinary platform for spatial multi-omic analysis of single cellsFrom1 Oct 2019 → 30 Sep 2023Funding: BOF - projects
- Transcriptional Mechanisms of Human-Specific Neuronal Differentiation and SpecificationFrom2 Sep 2019 → 2 Sep 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 177
- Mass Spectrometry of Flame Figures(2015)
Authors: Jasper Wouters, Etienne Waelkens, Siegfried Segaert, Joost van den Oord
Pages: 734 - 735 - First-in-Human Proof-of-Concept Study: Intralesional Administration of BQ788, an Endothelin Receptor B Antagonist, to Melanoma Skin Metastases(2015)
Authors: Jasper Wouters, Joost van den Oord
Pages: 1121 - 1122 - Prognostic and predictive biomarkers in melanoma: an update(2016)
Authors: Jasper Wouters
Pages: 223 - 237 - Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche(2016)
Authors: Olivier Govaere, Jasper Wouters, An Ceulemans, Frederik Nevens, Baki Topal, Hugo Vankelecom, Tania Roskams
Pages: 609 - 17 - KERATIN 19: A KEY ROLE PLAYER IN THE INVASION OF HUMAN HEPATOCELLULAR CARCINOMAS(2013)
Authors: Olivier Govaere, MIna Komuta, Joost Berkers, B Spee, Carl Janssen, F de Luca, A Katoonizadeh, Jasper Wouters, LC van Kempen, A Durnez, et al.
Pages: S430 - S430 - Keratin 19: a key role player in the invasion of human hepatocellular carcinomas(2014)
Authors: Olivier Govaere, MIna Komuta, Joost Berkers, Bart Spee, Carl Janssen, Francesca de Luca, Aezam Katoonizadeh, Jasper Wouters, Léon C van Kempen, Anne Durnez, et al.
Pages: 674 - 685 - Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes(2013)
Authors: Hugo Vankelecom, Wouter Van Delm, Jasper Wouters, Olivier Govaere, Tania Roskams, Baki Topal
- Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease(2022)
Authors: Olivier Govaere, Jasper Wouters, Matthias Van Haele, Baki Topal, Tania Roskams
Pages: 1001 - 1012 - A novel hypoxia-associated subset of FN1(high)MITF(low) melanoma cells: identification, characterization, and prognostic value(2014)
Authors: Jasper Wouters, Marguerite Stas, Olivier Govaere, Kathleen Barrette, Hugo Vankelecom, Joost van den Oord
Pages: 1088 - 1100 - Vision-related convergent gene losses reveal SERPINE3's unknown role in the eye(2022)
Authors: Nikolai Hecker