Organisation
Laboratory of Computational Biology (VIB-KU Leuven)
Division
Research in the Laboratory of Computational Biology is focusing on gene and genome regulation, with applications in Drosophila and cancer, and on integrative genomics, developing computational methods for genomic data integration and analysis of next-generation sequence data.
Projects
31 - 40 of 64
- Novel droplet-microfluidic solutions for single-cell multiomics.From1 Aug 2019 → 30 Sep 2023Funding: FWO Strategic Basic Research Grant
- Transcriptional circuitry of patterning of neural tube organoids and in vivo spinal cordFrom1 Feb 2019 → 30 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Mapping dynamic transcription factor hierarchies using pooled CRISPR screening with single-cell epigenome readoutFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- SymBioSys: Computationally disentangling cellular heterogeneityFrom1 Oct 2018 → 30 Sep 2022Funding: Fund Recuperation Fiscal Exemption
- Integrating genetic, environmental and developmental variation to study gene regulatory mechanismsFrom18 Jun 2018 → 5 Mar 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- EXPLORING THE CODE OF LIFE: FROM DECODING TO DESIGNING CELL TYPE-SPECIFIC ENHANCERS WITH DEEP LEARNINGFrom1 May 2018 → 19 Jul 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Single-cell omics in high throughput and at spatial resolutionFrom1 May 2018 → 30 Apr 2022Funding: FWO Medium Size Research Infrastructure
- Mapping regulatory landscapes in the Drosophila brain using single-cell microfluidsFrom11 Sep 2017 → 30 Nov 2022Funding: FWO fellowships
- Reverse engineering cellular identity at single cell resolutionFrom31 Aug 2017 → 7 Feb 2023Funding: FWO fellowships
- Decoding and controlling cell-state switching: A bottom-up approach based on enhancer logicFrom1 Jun 2017 → 31 May 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 177
- Mass Spectrometry of Flame Figures(2015)
Authors: Jasper Wouters, Etienne Waelkens, Siegfried Segaert, Joost van den Oord
Pages: 734 - 735 - First-in-Human Proof-of-Concept Study: Intralesional Administration of BQ788, an Endothelin Receptor B Antagonist, to Melanoma Skin Metastases(2015)
Authors: Jasper Wouters, Joost van den Oord
Pages: 1121 - 1122 - Prognostic and predictive biomarkers in melanoma: an update(2016)
Authors: Jasper Wouters
Pages: 223 - 237 - Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche(2016)
Authors: Olivier Govaere, Jasper Wouters, An Ceulemans, Frederik Nevens, Baki Topal, Hugo Vankelecom, Tania Roskams
Pages: 609 - 17 - KERATIN 19: A KEY ROLE PLAYER IN THE INVASION OF HUMAN HEPATOCELLULAR CARCINOMAS(2013)
Authors: Olivier Govaere, MIna Komuta, Joost Berkers, B Spee, Carl Janssen, F de Luca, A Katoonizadeh, Jasper Wouters, LC van Kempen, A Durnez, et al.
Pages: S430 - S430 - Keratin 19: a key role player in the invasion of human hepatocellular carcinomas(2014)
Authors: Olivier Govaere, MIna Komuta, Joost Berkers, Bart Spee, Carl Janssen, Francesca de Luca, Aezam Katoonizadeh, Jasper Wouters, Léon C van Kempen, Anne Durnez, et al.
Pages: 674 - 685 - Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes(2013)
Authors: Hugo Vankelecom, Wouter Van Delm, Jasper Wouters, Olivier Govaere, Tania Roskams, Baki Topal
- Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease(2022)
Authors: Olivier Govaere, Jasper Wouters, Matthias Van Haele, Baki Topal, Tania Roskams
Pages: 1001 - 1012 - A novel hypoxia-associated subset of FN1(high)MITF(low) melanoma cells: identification, characterization, and prognostic value(2014)
Authors: Jasper Wouters, Marguerite Stas, Olivier Govaere, Kathleen Barrette, Hugo Vankelecom, Joost van den Oord
Pages: 1088 - 1100 - Vision-related convergent gene losses reveal SERPINE3's unknown role in the eye(2022)
Authors: Nikolai Hecker