Organisation
Laboratory of Computational Biology (VIB-KU Leuven)
Division
Research in the Laboratory of Computational Biology is focusing on gene and genome regulation, with applications in Drosophila and cancer, and on integrative genomics, developing computational methods for genomic data integration and analysis of next-generation sequence data.
Projects
41 - 50 of 64
- Unravelling Single Cell Gene Regulatory Networks in DrosophilaFrom10 May 2017 → 30 Sep 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- Deciphering the genetic program of epithelial cellsFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Deciphering the regulatory code underlying a common epigenomic survival switch in cancerFrom1 Jan 2017 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
- Exploiting enhancer logic and transcriptional networks to control phenotype switching in melanomaFrom1 Oct 2016 → 14 Dec 2020Funding: FWO Strategic Basic Research Grant, Private funding of national origin - undefined
- Towards petascale biocomputational sciencesFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- Regulatory genomics of normal cell differentiation and cancer cell subpopulations in the same tissue of origin.From1 Oct 2014 → 11 Jun 2021Funding: IWT personal funding - strategic basic research grants
- Drosophila Allograft Screen to Identify cis-Regulatory Variation in Cancer Genomes.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Using photoreceptor differentiation in Drosophila as a model system in order to decipher how a developmental program is encoded in a metazoan genome.From1 Oct 2013 → 30 Sep 2017Funding: BOF - Concerted Research Project from 1994
- Drosophila allograft screen to identify cis-regulatory variation in cancer genomes.From1 Oct 2013 → 9 May 2018Funding: IWT personal funding - strategic basic research grants
- Identification of cancer driver mutations in the non-coding genome by integrative genomics and regulome sequencing.From1 Jan 2013 → 31 Dec 2016Funding: Private funding of national origin - undefined
Publications
1 - 10 of 177
- Mass Spectrometry of Flame Figures(2015)
Authors: Jasper Wouters, Etienne Waelkens, Siegfried Segaert, Joost van den Oord
Pages: 734 - 735 - First-in-Human Proof-of-Concept Study: Intralesional Administration of BQ788, an Endothelin Receptor B Antagonist, to Melanoma Skin Metastases(2015)
Authors: Jasper Wouters, Joost van den Oord
Pages: 1121 - 1122 - Prognostic and predictive biomarkers in melanoma: an update(2016)
Authors: Jasper Wouters
Pages: 223 - 237 - Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche(2016)
Authors: Olivier Govaere, Jasper Wouters, An Ceulemans, Frederik Nevens, Baki Topal, Hugo Vankelecom, Tania Roskams
Pages: 609 - 17 - KERATIN 19: A KEY ROLE PLAYER IN THE INVASION OF HUMAN HEPATOCELLULAR CARCINOMAS(2013)
Authors: Olivier Govaere, MIna Komuta, Joost Berkers, B Spee, Carl Janssen, F de Luca, A Katoonizadeh, Jasper Wouters, LC van Kempen, A Durnez, et al.
Pages: S430 - S430 - Keratin 19: a key role player in the invasion of human hepatocellular carcinomas(2014)
Authors: Olivier Govaere, MIna Komuta, Joost Berkers, Bart Spee, Carl Janssen, Francesca de Luca, Aezam Katoonizadeh, Jasper Wouters, Léon C van Kempen, Anne Durnez, et al.
Pages: 674 - 685 - Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes(2013)
Authors: Hugo Vankelecom, Wouter Van Delm, Jasper Wouters, Olivier Govaere, Tania Roskams, Baki Topal
- Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease(2022)
Authors: Olivier Govaere, Jasper Wouters, Matthias Van Haele, Baki Topal, Tania Roskams
Pages: 1001 - 1012 - A novel hypoxia-associated subset of FN1(high)MITF(low) melanoma cells: identification, characterization, and prognostic value(2014)
Authors: Jasper Wouters, Marguerite Stas, Olivier Govaere, Kathleen Barrette, Hugo Vankelecom, Joost van den Oord
Pages: 1088 - 1100 - Vision-related convergent gene losses reveal SERPINE3's unknown role in the eye(2022)
Authors: Nikolai Hecker