Publicaties
The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathology Universiteit Antwerpen
Pure progressive amnesia as variant of genetically proven Alzheimer disease Universiteit Antwerpen
Contributing to the elucidation of the genetic susceptibility of Alzheimer disease Universiteit Antwerpen
Molecular genetics of Alzheimer disease: an update Universiteit Antwerpen
Medische rijgeschiktheid : synthese en aanbevelingen van het symposium van de Koninklijke Academie voor Geneeskunde van België op 29 april 2023 Universiteit Gent
Verlaagt anti-Alzheimer medicatie het gebruik van andere psychofarmaca in woon- en zorgcentra? Universiteit Gent
Gezocht en gevonden Vrije Universiteit Brussel
Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations Vrije Universiteit Brussel KU Leuven Universiteit Antwerpen
BACKGROUND: The clusterin (CLU) gene has been identified as an important risk locus for Alzheimer's disease (AD). Although the actual risk-increasing polymorphisms at this locus remain to be identified, we previously observed an increased frequency of rare non-synonymous mutations and small insertion-deletions of CLU in AD patients, which specifically clustered in the β-chain domain of CLU. Nonetheless the pathogenic nature of these variants ...
Neutrophil Gelatinase-Associated Lipocalin and its Receptors in Alzheimer's Disease (AD) Brain Regions Vrije Universiteit Brussel Universiteit Antwerpen
Co-existing depression worsens Alzheimer's disease (AD) pathology. Neutrophil gelatinase-associated lipocalin (NGAL) is a newly identified (neuro)inflammatory mediator in the pathophysiologies of both AD and depression. This study aimed to compare NGAL levels in healthy controls, AD without depression (AD-D), and AD with co-existing depression (AD+D) patients. Protein levels of NGAL and its receptors, 24p3R and megalin, were assessed in nine ...