Publicaties
Development and partial validation of Be-CLIPSS Vrije Universiteit Brussel
BACKGROUND: Documentation of drug related problems (DRPs) and pharmaceutical interventions (PIs) is essential for an objective evaluation of the pharmacist's contribution to pharmacotherapy. However, in Belgium, a nationally used classification system is not available, prohibiting structured and uniform documentation of DRPs and PIs.
AIM: To develop and validate a national classification system for in-hospital clinical pharmacy ...
Immunosuppressive therapy management in cancer patients with autoimmune diseases treated with immune checkpoint inhibitors Vrije Universiteit Brussel
INTRODUCTION: Prescribing immune checkpoint inhibitors (ICIs) to cancer patients with an autoimmune disease (AID) is presumed safe when cautious adverse event management is applied. However, guidelines on immunosuppressant (IS) adaptations are limited and real-world evidence is scarce.
METHODS: Current practice of IS adaptations is described in a case series of AID patients treated with ICIs in a tertiary university hospital in ...
Introducing a pharmacist-led transmural care program to reduce drug-related problems in orthogeriatric patients Vrije Universiteit Brussel
Background: Orthogeriatric patients have an increased risk for complications due to underlying comorbidities, chronic drug therapy and frequent treatment changes during hospitalization. The clinical pharmacist (CP) plays a key role in transmural communication concerning polypharmacy to improve continuity of care by the general practitioner (GP) after discharge. In this study, a pharmacist-led transmural care program, tailored to ...
Clinical Decision Support and New Regulatory Frameworks for Medical Devices: Are We There Yet? A Response to the Recent Commentaries Vrije Universiteit Brussel
Using risk factors and markers to predict bacterial respiratory co-/superinfections in COVID-19 patients Vrije Universiteit Brussel
BACKGROUND: Adequate diagnosis of bacterial respiratory tract co-/superinfection (bRTI) in coronavirus disease (COVID-19) patients is challenging, as there is insufficient knowledge about the role of risk factors and (para)clinical parameters in the identification of bacterial co-/superinfection in the COVID-19 setting. Empirical antibiotic therapy is mainly based on COVID-19 severity and expert opinion, rather than on scientific evidence ...
Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways Vrije Universiteit Brussel
Advance care planning among older adults of Moroccan origin Vrije Universiteit Brussel
BACKGROUND: Advance care planning (ACP) is rare among ethnic minorities for social, cultural, and religious reasons.
AIM: To explore advance care planning-related knowledge, experience, and perspectives among adults aged ≥65 years with Moroccan backgrounds in Belgium.
METHOD: Semi-structured interviews were conducted in Darija (Moroccan Arabic). GPs in Brussels and Mechelen recruited participants. Data were analysed ...
Advance care planning among older adults with a Turkish background and palliative care needs Vrije Universiteit Brussel
BACKGROUND: Advance care planning is rare among older adults with a migration background because of social, cultural, and religious reasons.
AIM: To explore advance care planning-related knowledge and perspectives among older people from a Turkish background with palliative care needs living in Belgium.
METHOD: Semi-structured interviews were conducted in Turkish. Data were analysed using a combination of inductive and ...