Onderzoeker
Nora Pauwels
- Disciplines:Medicinale chemie niet elders geclassificeerd, Medicinale en biomoleculaire chemie niet elders geclassificeerd, Biomoleculaire modellering en design, Medicinale chemie, Moleculaire geneeskunde, Structurele biologie
Affiliaties
- Vakgroep Geneesmiddelenleer (Departement)
Lid
Vanaf1 sep 2008 → 21 sep 2014
Publicaties
1 - 10 van 10
- Synthesis of C-5" and C-6"-modified U+03B1-GalCer analogues as iNKT-cell agonists(2015)
Auteurs: Joren Guillaume, Nora Pauwels, Sandrine Aspeslagh, Dirk Zajonc
Pagina's: 3175 - 3182 - Synthesis of new U+03B1-GalCer analogues as iNKT cell targeting agents(2013)
Auteurs: Nora Pauwels
- Crystal structures of bovine CD1d reveal altered U+03B1GalCer presentation and a restricted A' pocket unable to bind long-chain glycolipids(2012)
Auteurs: Jing Wang, Joren Guillaume, Nora Pauwels, Ildiko Van Rhijn, Dirk M Zajonc
- Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis(2011)
Auteurs: Sandrine Aspeslagh, Yali Li, Esther Dawen Yu, Nora Pauwels, Matthias Trappeniers, Enrico Girard, Tine Decruy, Michael Drennan, Luc Leybaert, Jing Wang, et al.
Pagina's: 2294 - 2305 - Galactose modified iNKT cell agonists stabilised by a novel structural modification of CD1D lead to marked TH1 polarisation in vivo(2011)Volume: 70
Auteurs: Sandrine Aspeslagh, YaLi Li, Esther Dawen Yu, Nora Pauwels, Matthias Trappeniers, Enrico Girardi, Tine Decruy, Katrien Van Beneden, Koen Venken, Michael Drennan, et al.
Pagina's: A53 - A53 - 6''-Modified alpha-GalCer analogs capable of establishing an extra interaction with Cd1d leading to a polarized Th1 response and superior tumor protection(2011)Volume: 241
Auteurs: Serge Van Calenbergh, Nora Pauwels, Sandrine Aspeslagh, YaLi Li, Matthias Trappeniers, Dirk Zajonc, Dirk Elewaut
Aantal pagina's: 1 - Synthesis of 6U+201D-triazole-substituted U+03B1-GalCer analogues as potent iNKT cell stimulating ligands
Auteurs: Nora Pauwels, Sandrine Aspeslagh
Pagina's: 7149 - 7154 - Versatile synthesis of C-5" and C-6"-modified U+03B1-GalCer analogues as new iNKT cell ligands
Auteurs: Nora Pauwels, Sandrine Aspeslagh
Pagina's: 63 - 63 - Lipid and carbohydrate modifications of U+03B1-galactosylcer-amide differently influence mouse and human type I natural killer T cell activation
Auteurs: Alysia Birkholz, Marek Nemcovic, Esther Dawen Yu, Enrico Girardi, Jing Wang, Archana Khurana, Nora Pauwels, Elisa Farber, Sampada Chitale, Richard W Franck, et al.
Pagina's: 17206 - 17217 - Divergent synthetic approach to 6''-modified U+03B1-GalCer analogues
Auteurs: Nora Pauwels, Sandrine Aspeslagh, Gerd Vanhoenacker, Koen Sandra, Esther D Yu, Dirk M Zajonc, Bruno Linclau
Pagina's: 8413 - 8421