Researcher
Nora Pauwels
- Disciplines:Medicinal chemistry not elsewhere classified, Medicinal and biomolecular chemistry not elsewhere classified, Biomolecular modelling and design, Medicinal chemistry, Molecular medicine, Structural biology
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Sep 2008 → 21 Sep 2014
Publications
1 - 10 of 10
- Synthesis of C-5" and C-6"-modified U+03B1-GalCer analogues as iNKT-cell agonists(2015)
Authors: Joren Guillaume, Nora Pauwels, Sandrine Aspeslagh, Dirk Zajonc
Pages: 3175 - 3182 - Synthesis of new U+03B1-GalCer analogues as iNKT cell targeting agents(2013)
Authors: Nora Pauwels
- Crystal structures of bovine CD1d reveal altered U+03B1GalCer presentation and a restricted A' pocket unable to bind long-chain glycolipids(2012)
Authors: Jing Wang, Joren Guillaume, Nora Pauwels, Ildiko Van Rhijn, Dirk M Zajonc
- Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis(2011)
Authors: Sandrine Aspeslagh, Yali Li, Esther Dawen Yu, Nora Pauwels, Matthias Trappeniers, Enrico Girard, Tine Decruy, Michael Drennan, Luc Leybaert, Jing Wang, et al.
Pages: 2294 - 2305 - Galactose modified iNKT cell agonists stabilised by a novel structural modification of CD1D lead to marked TH1 polarisation in vivo(2011)Volume: 70
Authors: Sandrine Aspeslagh, YaLi Li, Esther Dawen Yu, Nora Pauwels, Matthias Trappeniers, Enrico Girardi, Tine Decruy, Katrien Van Beneden, Koen Venken, Michael Drennan, et al.
Pages: A53 - A53 - 6''-Modified alpha-GalCer analogs capable of establishing an extra interaction with Cd1d leading to a polarized Th1 response and superior tumor protection(2011)Volume: 241
Authors: Serge Van Calenbergh, Nora Pauwels, Sandrine Aspeslagh, YaLi Li, Matthias Trappeniers, Dirk Zajonc, Dirk Elewaut
Number of pages: 1 - Synthesis of 6U+201D-triazole-substituted U+03B1-GalCer analogues as potent iNKT cell stimulating ligands
Authors: Nora Pauwels, Sandrine Aspeslagh
Pages: 7149 - 7154 - Versatile synthesis of C-5" and C-6"-modified U+03B1-GalCer analogues as new iNKT cell ligands
Authors: Nora Pauwels, Sandrine Aspeslagh
Pages: 63 - 63 - Lipid and carbohydrate modifications of U+03B1-galactosylcer-amide differently influence mouse and human type I natural killer T cell activation
Authors: Alysia Birkholz, Marek Nemcovic, Esther Dawen Yu, Enrico Girardi, Jing Wang, Archana Khurana, Nora Pauwels, Elisa Farber, Sampada Chitale, Richard W Franck, et al.
Pages: 17206 - 17217 - Divergent synthetic approach to 6''-modified U+03B1-GalCer analogues
Authors: Nora Pauwels, Sandrine Aspeslagh, Gerd Vanhoenacker, Koen Sandra, Esther D Yu, Dirk M Zajonc, Bruno Linclau
Pages: 8413 - 8421