Projects
Otoscopic profilometry: a new optical technique to quantitatively measure human eardrum deformation in-vivo, in 3D and in real-time. University of Antwerp
Quantitative automatic analysis of confocal digital images of the cornea Ghent University
This proposal aims to develop and validate algorithms for image quality improvement, segmentation and extraction of clinically relevant parameters, for automated quantitative analysis of confocal digital images of the cornea. This is done to reduce the analysis time and to avoid subjective errors associated with manual, or a semi-automatically work made by the medical specialist.
A high-throughput quantitative study of the early embryonic cell cycle KU Leuven
'Molecular Imaging' meets 'Imaging Molecules' University of Antwerp
Molecular Imaging Center Antwerp - Bio-Imaging Lab (MICA-BIL). University of Antwerp
Fluorine-19 Magnetic Resonance Imaging as a Potential Tool in Preclinical Research --- With Focus on Diabetes KU Leuven
Diabetes remains one of the increasing threats to human health with over 422 million people suffering from the disease all over the world. Despite the advancements in understanding the disease and improvements in treatment, diagnosis and early prevention with effective monitoring of pre- and post- therapy of the disease is still urgently needed. Hereby, the function and mass of pancreatic islets (PIs) and in particular their beta cells play ...
"Dosimetry aspects of recoiling daughter nuclides of 225-Actinium in Targeted Alpha Therapy" KU Leuven
Targeted Radionuclide Therapy (TRNT) is a promising treatment for disseminated and metastatic diseases using a targeting agent labeled with a radionuclide delivering a toxic level of radiation to a specific site. DOTATATE labeled with beta-emitter radionuclides has been widely used in the clinic for peptide receptor radionuclide therapy (PRRT), mostly in the form of 177Lu-DOTATATE to treat neuroendocrine tumors. In this context, 68Ga-DOTATATE ...
Advancing biomechanical profiling of musculoskeletal system from structure to function. KU Leuven
My research focuses on bridging my engineering background towards the functional profiling of the human locomotor system in health and disease. Through the integration of in-vitro, in-silico and in-vivo, clinical research, I aim to identify key biomechanical parameters and anatomical features that define the optimal functioning of the musculoskeletal system. Through my close collaborations with clinicians and the medical device industry, I ...
Whole genome and RNA sequencing for platelet disorders KU Leuven
This project aims to deliver a rapid stem cell-based model to study known (but functionally undefined) and novel genes using CRISPR/Cas technology, quantitative in vivo imaging and genetic studies. Novel genes will be obtained from WGS data obtained for undiagnosed patients with very well-known platelet disorders, supplemented with platelet transcriptomes. This will allow WGS data analysis of differentially expressed genes. Validated novel ...