Impact of ZEB2 on specification, zonation and regeneration of liver sinusoidal endothelium KU Leuven
Liver sinusoidal endothelial cells (LSECs) are a highly specialized type of endothelial cells (ECs) characterized by a high permeability due to the presence of transcellular pores, called fenestrations, a poorly developed basement membrane, and high expression levels of scavenger receptors. Due to this high permeability and their position at the interface between blood and hepatocytes, LSECs act as a selective filter of the blood, allowing ...