Researcher
Annemieke Madder
- Keywords:protein modification, peptides, oligonucleotides, bioorthogonal conjugation
- Disciplines:Organic chemical synthesis, Food chemistry, Bio-organic chemistry, Drug discovery and development not elsewhere classified, Biomolecular modelling and design, Medicinal and biomolecular chemistry not elsewhere classified
Affiliations
- Department of Organic and Macromolecular Chemistry (Department)
Member
From1 Oct 1993 → Today
Projects
1 - 10 of 63
- Antibody-oligonucleotide conjugation for cellular delivery of oligonucleotidesFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- Furan and porphyrin containing crosslinking ligands for covalent stabilisation of G quadruplexes as cell-permeable anti-cancer aptamersFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- ReHiFiNMR - Rejuvenation of High-Field NMR equipment for the continued and enhanced characterization of complex molecular architectures and their interactionsFrom1 May 2024 → TodayFunding: FWO Medium Size Research Infrastructure
- A MALDI-TOF/TOF MS instrument for (bio)polymer characterization and imaging.From1 May 2024 → TodayFunding: FWO Medium Size Research Infrastructure
- A combined structure-activity and biophysical investigation of the cyclic lipopeptide tolaasin, the virulence factor causing brown blotch diseaseFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Cofunding core facility - NMR Expertise CentreFrom1 Oct 2023 → TodayFunding: BOF - research organisations
- A combined structure-activity and biophysical investigation of the cyclic lipopeptide tolaasin, the virulence factor causing brown blotch diseaseFrom1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Synthetic antibody (SynAb) receptors for the detection and isolation of cyclic depsipeptide (CDP) toxins in food samples.From1 Apr 2023 → TodayFunding: BOF - various, HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- A new photoelectrochemical singlet oxygen-based detection platform for a panel of cancer biomarkers in tissue and liquid biopsies (SOCAN)From1 Jan 2023 → TodayFunding: BOF - iBOF
- Routine NMR Analysis Equipment for Small Molecule Characterisation.From15 Dec 2022 → TodayFunding: BOF - scientific equipment program
Publications
1 - 10 of 248
- Time-resolved fluorescence of tryptophan characterizes membrane perturbation by cyclic lipopeptides(2024)
Authors: Iulia Carabadjac, Jessica Steigenberger, Niels Geudens, Vic De Roo, Penthip Muangkaew, Annemieke Madder, José Martins, Heiko Heerklotz
Pages: 2557 - 2573 - Sustained release of a human PD-L1 single-domain antibody using peptide-based hydrogels(2024)
Authors: Julie Heremans, Robin Maximilian Awad, Jessica Bridoux, Thomas Ertveldt, Vicky Caveliers, Annemieke Madder, Richard Hoogenboom, Nick Devoogdt, Steven Ballet, Sophie Hernot, et al.
- Photo-induced crosslinking uncovers an antiparallel strand orientation in heterodimeric (EIAALEK)(3)/(KIAALKE)(3) and (EIAALEK)(3)/(RIAALRE)(3) coiled-coil systems(2023)
Authors: Dorien Aerssens, Laia Miret Casals, D. Gomez, D. Sousa-Neves, Y. Levy, M. De Vleesschouwer, Alex Manicardi, Annemieke Madder
Pages: 5648 - 5657 - Proximity-induced ligation and one-pot macrocyclization of 1,4-diketone-tagged peptides derived from 2,5-disubstituted furans upon release from the solid support(2023)
Authors: Alex Manicardi, Atiruj Theppawong, Marleen Van Troys, Annemieke Madder
Pages: 6618 - 6622 - Unlocking the secrets of aptamer-small molecule complexes through NMR spectroscopy(2023)
Authors: Sofie Schellinck, Nataša Medved, Dieter Buyst, Karolien De Wael, Annemieke Madder, Janez Plavec, José Martins
Number of pages: 1 - Furan-based (photo)oxidation reactions and their application in nucleic acid and protein targeting(2023)
Authors: Jack Barr, Gertjan Colpaert, Enrico Cadoni, Annemieke Madder
Pages: 189 - 197 - A red light-triggered chemical tool for sequence-specific alkylation of G-quadruplex and I-motif DNA(2023)
Authors: Enrico Cadoni, Lessandro De Paepe, Gertjan Colpaert, Ruben Tack, Alex Manicardi, Annemieke Madder
Pages: 4112 - 4125 - Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions(2023)
Authors: Helena Braet, Peter-Paul Fransen, Yong Chen, Simon Van Herck, Remco Mariën, Valérie Vanhoorne, Wim Ceelen, Annemieke Madder, Steven Ballet, Richard Hoogenboom, et al.
Pages: 138 - 150 - Development of teixobactin analogues containing hydrophobic, non-proteogenic amino acids that are highly potent against multidrug-resistant bacteria and biofilms(2023)
Authors: Anish Parmar, Rajamani Lakshminarayanan, Abhishek Iyer, Eunice Tze Leng Goh, Tsz Ying To, Joey Kuok Hoong Yam, Liang Yang, Enas Newire, Maria C. Robertson, Stephen H. Prior, et al.
- Furan-modified PNA probes for covalent targeting and ligation of nucleic acids(2023)
Authors: Lessandro De Paepe, Enrico Cadoni, Alex Manicardi, Annemieke Madder
Pages: 210 - 223
Patents
1 - 10 of 10
- Hydrogel-forming composition for controlled released (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Hydrogel-forming peptides (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- Hydrogel-forming peptides (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Synthetic receptors for ionophoric compounds (Inventor)