Projects
Formulation and processing of probiotic bacteria in a solid oral dosage form for pharyngeal delivery. University of Antwerp
Fermented vegetable juices – Microbiome analysis and their probiotic potential? University of Antwerp
Microbiome analysis of the upper respiratory tract: identification of beneficial microbes with probiotic potential. University of Antwerp
The influence of probiotic watercontent and wateractivity in spray-dried nasopharyngeal and buccal formulations. University of Antwerp
Polygenic analysis of the unique antibiotic potency of high acetic acid production and evaluation of other probiotic traits in Saccharomyces cerevisiae var. boulardii KU Leuven
The World Health Organisation (WHO) as well as the Food and Agricultural Organisation (FAO) define probiotics as live micro-organisms that confer a beneficial health effect on a host when they are administered in adequate quantities. Most probiotics are bacteria belonging to the genera Lactobacilli and Bifidobacteria. However, one of the most popular probiotics is the yeast Saccharomyces cerevisiae var. boulardii (S. ...
Assessment of safety and colonization potential of well characterized probiotic strains in South African women with healthy and disturbed vaginal microflora by molecular methods Ghent University
Alterations in the vaginal microbiome contribute to risk of preterm birth and increased transmission of sexually transmitted agents and HIV-mother-to-child-transmission. Exogenous supplementation of vaginal bacteria to maintain and restore a healthy vaginal microflora could lead to important intervention strategies. In this project different molecular methods will be applied to study how probiotic bacteria can influence the vaginal ...
Glycoproteins in probiotic bacteria: exploring the glycosylation potential of Lactobacillus rhamnosus GG (LGG) by genomics and glycoproteomics. KU Leuven
A wide variety of glycoconjugates covers the cell wall of prokaryotes, forming a unique species-specific barcode. These glycoconjugates are important to establish specific interactions with the environment. Most studies of bacterial glycobiology focus on pathogens. Here, the importance of glycosylation in the microbiota isolate and model probiotic strain Lactobacillus rhamnosus GG is investigated, with a focus on glycoproteins. To ...
The Lactobacillus rhamnosus GG Embp adhesin as a gateway for new formulations in the probiotic market. KU Leuven
Probiotic administration as add-on therapy in ulcerative colitis and pouchitis Ghent University
A probiotic strain (Bifidobacterium breve UCP0911) was selected with anti-inflammatory properties and hence, important potential in the treatment of inflammatory bowel disease (IBD). During well-designed clinical trials, the potential of the selected probiotic in IBD patients (ulcerative colitis and pouchitis) will be fully explored. These clinical trials will aim at unravelling the basic interaction between microbial, immunological and ...