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Project
The influence of probiotic watercontent and wateractivity in spray-dried nasopharyngeal and buccal formulations.
This project investigates how the critical formulation and process parameters influence the zeta-potential and the wateractivity in nasal/buccal sprays and lozenges of spray-dried probiotics, in particular with Lactobacillus rhamnosus species. The link between wateractivity, absolute water content and cell viability will be investigated immediately after production and in a stability study.
Date:1 Feb 2014 → 31 Dec 2014
Keywords:NASAL SPRAY, PROBIOTIC TREATMENT, WATER ACTIVITY, FORMULATION
Disciplines:Other chemical sciences, Nutrition and dietetics, Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Agricultural animal production, Food sciences and (bio)technology