Projects
Inverse Kinematic Alignment for Total Knee Arthroplasty The Concept, Clinical Outcomes and Biomechanical Outcomes KU Leuven
Knee arthroplasty is a frequently performed surgical procedure for the treatment of end stage knee osteoarthritis. Postoperative function and patient satisfaction are becoming increasingly relevant in knee arthroplasty. Despite adequate preoperative planning and improved surgical techniques and rehabilitation protocols, only 75%-85% of patients seem satisfied after mechanically aligned total knee arthroplasty (TKA). Unicompartmental knee ...
Structural nested models for the effect of a time-varying exposure on dichtomous outcomes and survival outcomes Ghent University
Estimation of the effect of time-varying exposure on a given outcome is typically plagued by the presence of time-varying confounders. Because standard regression adjustment for such confounders is fallible, the goal of the proposed research is to overcome this through the development of structural nested models for outcomes that are dichotomous or survival times.
The role of GLucose homeostasis and metabOlomics in pregnancy outcomes afteR barIAtric surgery: the GLORIA study. KU Leuven
Glucose homeostasis, metabolomics and pregnancy outcomes after bariatric surgery: the GLORIA study The prevalence of obesity and metabolic syndrome is increasing at an alarming rate worldwide. Obesity in women is associated with infertility and miscarriages. During pregnancy, obesity is associated with increased risk of gestational diabetes mellitus (GDM), preeclampsia, macrosomia and caesarean delivery. For women with a body mass index (BMI) ...
Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement KU Leuven
Optimal treatment of the impaired mobility resulting from ageing and chronic disease is one of the 21st century's greatest challenges facing patients, society, governments, healthcare services, and science. New interventions are a key focus. However, to accelerate their development, we need better ways to detect and measure mobility loss. Digital technology, including body worn sensors, has the potential to revolutionise mobility assessment. ...
‘OBI-CATCH’, maternal OBesity and outcomes in next generations, Impact of innovative lifestyle interventions to CATCH maternal, paternal and childhood obesity KU Leuven
Do schools and teachers leave their mark? Studies on long-term effects of schools and teachers on student outcomes KU Leuven
In the field of educational effectiveness research, teacher and school effects are most often studied in the short term. Long-term school and teacher effects are less often studied and the findings are inconsistent. The objective of this dissertation is to study long-term school and teacher effects. The main question is: do schools or teachers still influence students’ outcomes at the moment these students already changed school or teacher? ...
Serious games: development of a standard for measuring the effectiveness of games in terms of cognitive learning outcomes Ghent University
1. Introduction
A large heterogeneity in study designs assessing the effectiveness of digital game-based (DGBL) and questions raised regarding reliability and validity of certain study design characteristics has resulted in a need for a more common methodology. The aim of this Ph.D. project was to develop a standardized procedure for assessing the effectiveness of DGBL, with a primary focus on games that target cognitive learning ...
An analysis of the impact of acute and chronic heat stress on various health outcomes using a distributed lag non-linear model and Bayesian spatio-temporal approach KU Leuven
According to the World Meteorological Organization (WMO), 2015-2022 are the eight consecutive warmest year. As a result of continual climate change over many years, there is an increasing trend in temperature, the frequency and intensity of extreme weather events. In light of global warming and climate change, studying the impact of extended temperature over many years on both morbidity and mortality for pronounced future course of practical ...