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Researcher

Thomas Vanwolleghem

  • Research Expertise:Main research topics: Virus-Host interactions, public health and clinical outcomes in viral hepatitis. We aim to study, guide and improve clinical outcomes of patients with viral hepatitis, by analyzing morbidity/mortality and pathophysiology, at a clinical and cellular level with clinical trials, patient registries and state of the art translational approaches in well-characterized patient samples both from liver and blood We examine the cascade of care in patients with chronic HBV and HCV infections, by outreach screening activities in ethnic minorities both in Belgium as in Uganda We study virus-host interactions in HBV and HEV infections by applying multiparametric approaches using Flowcytometry, Multiplex/ELISPOT, Micro-array/RNA sequencing and a liver humanized small animal model
  • Keywords:TRANSCRIPTOMICS, IMMUNOLOGY, LIVER DISEASE, VIRAL HEPATITIS, CLINICAL OUTCOME, Medicine
  • Disciplines:Bioinformatics and computational biology, Gastro-enterology and hepatology, Immunology, Medical systems biology, Microbiology
  • Research techniques:We examine the sero-epidemiology as well as clinical outcomes and the cascade of care in patients with HBV, HCV, HDV or HEV infections. We perform outreach screening activities towards HBV/HCV infections in ethnic minorities both in Belgium as in Uganda We study virus-host interactions in HBV, HCV and HEV infections by applying multiparametric approaches using Flowcytometry, Multiplex/ELISPOT, Micro-array/RNA sequencing and a liver humanized small animal model
  • Users of research expertise:- Researchers with a specific interest in virus-host interactions, including cell culture, flowcytometric and RNA sequencing (including single cell) approaches focused on liver diseases - Researchers interested in sero-epidemiology studies of hepatitis viruses - Researchers interested in clinical outcomes studies of hepatitis viruses