Projects
ATMP Center: custom quality control & GMP services for clinical ATMP development Hasselt University
Multi-omics approach to identify pancreatic cancer biomarkers in liquid biopsies of advanced stage patients by pioneering single cell mass spectrometry of CTCs and (epi)genetics characterization of cfDNA Ghent University
Pancreatic cancer is a deadly disease with surgery the only chance for cure. Surgeons have to evaluate whether patients with advanced pancreatic cancer will benefit from surgery. Current diagnostic tools (imaging and CA19-9), are inadequate, with early recurrence and metastases seen in up to 40% of patients. To address this, a multi-omics approach is proposed to identify PDAC biomarkers in liquid biopsies with higher accuracy, sensitivity, ...
Identification of universal biomarkers of metastatic melanoma in CTCs KU Leuven
Cutaneous melanoma is the most aggressive form of skin cancer and is notorious for its high metastatic propensity. Melanoma cells disseminate by gaining access to the bloodstream, where they are detectable as Circulating Tumor Cells (CTCs), a subpopulation that constitutes the seeds for metastases and thereby responsible for the vast majority of melanoma-related deaths. The detection and analysis of CTCs can therefore assist early patient ...
EF-27 Follow-up data analysis BelRAI LTCF KU Leuven
Follow-up study data analysis BelRAI LTCF pilot project EF06.06(3)
EJP RD JTC: Quality of life of patients living with vascular LIVEr diseaseS Developing research on the social impact of rare diseases Vrije Universiteit Brussel
care needs, uncertain prognosis, side effects of treatments, with an overall impact on their work
or personal life, especially when they are still young and professionally active. However, data on
their Quality of life (QoL) are still scarce and focus on disease-related variables, failing to
incorporate the social and the ...
ATMP Logistics (Advanced Therapy Medicinal Products) VIL - Flanders Innovation Cluster for Logistics
ATMP Logistics
In the pharmaceutical sector, a streamlined process from A to Z is the key to success, especially in the case of Advanced Therapy Medicinal Products (ATMP). The logistics of this distinct group of medicines is complex because of the specific requirements regarding temperature, reliability and traceability. With the ATMP Logistics project, VIL aims to provide an answer to these challenges.
Distribution ...
Creating Sub-18 nm pitch EUV lithography and plasma etch transfer processes for next-generation device technologies KU Leuven
The study is a PhD position at KU Leuven in collaboration with imec, Heverlee. The topic of the position is 'Creating sub 18-nanometer pitch EUV lithography and plasma etch transfer processes for next-generation device technologies '. There are two main facets to this project - 'Lithography' and 'Plasma etch transfer process'. Both of these lie at the heart of semiconductor manufacturing for information and communications technology (ICT) ...
Ion channel modulators to treat itch Ghent University
Chronic itch can be devastating to such an extent that some patients report a willingness to accept a shorter lifespan in return for an alleviating treatment. Itch, or pruritis, is commonly
associated with a primary skin disorder; however, in a substantial subset of patients, pruritis originates from an unknown origin. Even though pruritus occurs in nearly 20% of adults,
treatment options are typically limited to over-the-counter ...
Nav1.9 participation in chronic itch Ghent University
Even though the scientific community is in virtual agreement on a prominent contribution of Nav19 (gene name: SCN11A) to pain, the role of this voltage-gated sodium (Nav) channel subtype in itch is virtually unknown Yet, patients with a Nav19 pL811P mutation consistently report debilitating chronic itch Our previous work uncovered a role for Nav19 in transmitting acute itch signals via peripheral nerves, likely via a subset of prurinergic ...