Researcher
Kathleen Claes
- Keywords:inherited predisposition for cancer
- Disciplines:Immunogenetics, Clinical genetics and molecular diagnostics, Epigenetics, Genetics, Cancer prevention, Cancer diagnosis, Oncology not elsewhere classified, Molecular diagnostics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Mar 1997 → 30 Sep 2018
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 16
- Multi-omics approach to identify pancreatic cancer biomarkers in liquid biopsies of advanced stage patients by pioneering single cell mass spectrometry of CTCs and (epi)genetics characterization of cfDNAFrom1 Oct 2023 → TodayFunding: BOF - projects
- Joint Action on Networks of ExpertiseFrom1 Oct 2022 → TodayFunding: Other EU initiatives out of framework
- Cofunding core facility - UGent NGS CoreFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- In vivo functional evaluation of unclassified variants, found in the breast cancer gene BRCA2, using CRISPR-mediated genome editing in zebrafishFrom15 Nov 2021 → TodayFunding: BOF - doctoral mandates
- Diagnosing HEreditary predisposition syndromes for Childhood cancer: Implementation in clinical PRactice (DHECIPR)From1 Jan 2021 → TodayFunding: FWO Applied Biomedical Research (TBM)
- CONDITIONAL: COvid-19: iNterplay between genetic preDisposITION and immunologicAl LandscapeFrom15 Apr 2020 → 14 Apr 2021Funding: BOF - projects
- Heading towards an in vivo predictive test for personalized ovarian cancer treatment: application of novel therapies in zebrafish patient derived xenograftsFrom1 Nov 2019 → TodayFunding: FWO Strategic Basic Research Grant
- RAPID - Radiosensitivity Analysis for patients with a Primary Immunodeficiency DiseaseFrom1 Oct 2018 → 30 Sep 2022Funding: FWO Applied Biomedical Research (TBM)
- Immunomonitoring of patients with non-small cell lung carcinoma treated with a tumor mutanome-targeted dendritic cell vaccineFrom1 Jan 2018 → 31 Dec 2021Funding: BOF - Doctoral projects
- Pancreatic cancer: hope to improve prognosis through thorough analysis of DNA and RNA markers for diagnosis and therapy monitoring in liquid biopsiesFrom1 Sep 2017 → 31 Dec 2023Funding: Nonprofit institution or equivalents
Publications
1 - 10 of 80
- The psychological impact of genetic testing in childhood cancer : a systematic review(2024)
Authors: Sophie Van Hoyweghen, Kathleen Claes, Robin de Putter, Claire Wakefield, Marieke Van Schoors, Sabine Hellemans, Lesley Verhofstadt
- A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment(2023)
Authors: Elly De Vlieghere, Koen Van de Vijver, Eva Blondeel, Nathan Carpentier, Rouba Ghobeira, Jarne Pauwels, Sebastian Riemann, Manon Minsart, Charlotte Fieuws, Johanna Mestach, et al.
- Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2(2023)
Authors: Denise G. O’Mahony, Susan J. Ramus, Melissa C. Southey, Nicola S. Meagher, Andreas Hadjisavvas, Esther M. John, Ute Hamann, Evgeny N. Imyanitov, Irene L. Andrulis, Priyanka Sharma, et al.
Pages: 2283 - 2294 - HRAS-related epidermal nevus syndromes : expansion of the spectrum with first branchial arch defects(2023)
Authors: Aude Beyens, Charlotte Lietaer, Kathleen Claes, Elfride De Baere, Marleen Goeteyn, Bob Lerut, Hannes Syryn, Olivier Vanakker, Joni Van der Meulen, Lieve Vanwalleghem, et al.
Pages: 709 - 713 - Noncoding aberrations in mismatch repair genes underlie a substantial part of the missing heritability in Lynch syndrome(2022)
Authors: Iris B.A.W. Te Paske, Arjen R. Mensenkamp, Kornelia Neveling, Nicoline Hoogerbrugge, Marjolijn J.L. Ligtenberg, Richarda M. De Voer, Stéphanie Baert-Desurmont, Kathleen Claes, Kim De Leeneer, Lisa Elze, et al.
Pages: 1691 - 1694.e7 - Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers(2022)
Authors: Christopher Hakkaart, John F. Pearson, Louise Marquart, Joe Dennis, George A. R. Wiggins, Daniel R. Barnes, Bridget A. Robinson, Peter D. Mace, Kristiina Aittomäki, Irene L. Andrulis, et al.
- Belgian guidelines for the frequency of participation of the Medical Centers of Human Genetics to external quality assessment schemes for analyses focused on rare diseases(2022)Volume: 30
Authors: Josephine Lantoine, Anne Brysse, Vinciane Dideberg, Kathleen Claes, Sofie Symoens, Wim Coucke, Valerie Benoit, Sonia Rombout, Martine De Rycke, Sara Seneca, et al.
Pages: 472 - 472 - Breast and prostate cancer risks for male BRCA1 and BRCA2 pathogenic variant carriers using polygenic risk scores(2022)
Authors: Daniel R Barnes, Valentina Silvestri, Goska Leslie, Lesley McGuffog, Joe Dennis, Xin Yang, Julian Adlard, Bjarni A Agnarsson, Munaza Ahmed, Kristiina Aittomäki, et al.
Pages: 109 - 122 - TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C(2022)
Authors: Levi Hoste, Lisa Roels, Leslie Naesens, Victor Bosteels, Stijn Vanhee, Sam Dupont, Cédric Bosteels, Robin Browaeys, Niels Vandamme, Kevin Verstaen, et al.
- Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants : application of a points-based ACMG/AMP approach(2022)
Authors: M Thomassen, RLS Mesman, TVO Hansen, M Menendez, M Rossing, A Esteban-Sánchez, E Tudini, T Törngren, MT Parsons, IS Pedersen, et al.
Pages: 1921 - 1944