Relevance of an altered epithelial function in gastrointestinal and non-gastrointestinal disorders KU Leuven
The intestinal barrier separates the internal environment from the lumen of the gastrointestinal (GI) tract. To keep the normal epithelial homeostasis (absorption of nutrients and water, water secretion…) a tight epithelial regulation is essential. Luminal components cross the intestinal barrier through the cells (transcellular pathway), or between the cells (paracellular pathway). During this project, we will explore the role of altered ...