Projects
Selective Modifications of ARomatics through Biocatalytic Oxidations KU Leuven
Although they have the potential to improve the economic and environmental sustainability of biorefineries, oxidative enzymes have not experienced a complete breakthrough yet in the biobased industries. This is mainly caused by the high cost and long time associated with traditional enzyme engineering methods such as directed evolution. SMARTBOX will develop an advanced computational engineering platform specifically for oxidative enzymes, ...
Digital microfluidic lab-on-a-chip for biosensor technology and (bio)catalysis. KU Leuven
High-value products from flaxseed through innovative biocatalytic technologies Research Institute for Agriculture, Fisheries and Food
The worldwide growing demand for flax fibers has resulted in a marked increase in flax acreage in Flanders and Europe. For every ton of long flax fibers, 0.7 tons of linseed is produced in Belgium, which is considered a by-product, of which 30-40% is oil used mainly for lower-end technical applications. The residual fraction after extraction of the linseed oil is used as animal feed. In this ...
DeoxyBioCat: Unlocking Synthetic Biology of Deoxy Sugars via Redesigned Biocatalytic Cascades Ghent University
Deoxysugars are special carbohydrates lacking at least one hydroxy
group. They are important building blocks and recognition sites in
functional oligosaccharides, glycoconjugates and natural glycosides
(e.g. antibiotics), in which they often critically affect bioactivity.
Deoxygenation of common sugars typically happens at nucleotide
sugar level and is catalyzed by 4,6-dehydratases that belong to the ...
Turning sucrose synthase into a biocatalyst for the production of nucleotide sugars Ghent University
Glycosyltransferases are extremely efficient enzymes but require expensive nucleotide sugars as glycosyl donor. The current proposal aims to solve this problem by producing these compounds from sucrose (and analogues) as a cheap
and reactive substrate, using (mutant) sucrose synthase as biocatalyst.
High-value products from flaxseed through innovative biocatalytic technologies Karel De Grote Hogeschool
A key role of bio-analysis in guiding thiamine biofortification and thiamine biomonitoring 'in the field'. Ghent University
Thiamine plays an essential role in energy metabolism. Humans have to rely on their diet for its
supply. Thiamine deficiency mainly affects developing countries, primarily as a result of the lack of
a varied diet, where some may largely depend on e.g. rice, which is low in thiamine content, for
their energy supply. Knowledge on the prevalence of this deficit in developing countries is limited
due the difficulty of ...
Emergency request for approval of funds for bio-analysis of food and urine samples for suspected mycotoxins. Ghent University
The United Republic of Tanzania notified WHO of a suspected outbreak of acute aflatoxicosis on 15 June 2016 currently affecting Dodoma and Manyare regions with 53 cases and 13 deaths reported as of 18 July 2016. Preliminary laboratory testing of food by Tanzania Food and Drugs Authority collected from the affected areas has revealed high levels of aflatoxin, suggesting that the outbreak was caused by aflatoxin poisoning. In addition a limited ...
BioCatGluCans: Biocatalytic production of beta-glucans Ghent University
This project focuses on the research and development of a new process for the enzymatic production (phosphorylase-mediated) and isolation of α -glucose 1-phosphate (G-1-P) and specific β glucans ( ~ -G) with industrial relevance, wherein maltodextrins warden used as the main substrate.