Researcher
Tom Desmet
- Keywords:biocatalysis, enzyme engineering, carbohydrate biotechnology
- Disciplines:Other biotechnology, bio-engineering and biosystem engineering not elsewhere classified, Medical biotechnology not elsewhere classified, Industrial molecular engineering of nucleic acids and proteins, Cell, tissue and organ engineering, Cellular therapy, Gene and molecular therapy, Genetically modified animals , Carbohydrates, Biocatalysis and enzyme technology
Affiliations
- Department of Biotechnology (Department)
Member
From1 Jan 2018 → Today - Department of Biochemical and microbial technology (Department)
Member
From1 Apr 2006 → 31 Dec 2017 - Department of Biochemistry and microbiology (Department)
Member
From1 Jan 2001 → 31 Mar 2006
Projects
1 - 10 of 30 results
- Automated protein purification: an essential step towards further analyses and new applications.From1 Dec 2020 → TodayFunding: BOF - scientific equipment program
- Unlocking Synthetic Biology of Deoxy Sugars via Enzyme Engineering and Biocatalytic CascadesFrom1 Nov 2020 → TodayFunding: BOF - doctoral mandates
- Phosphorylases as cost-efficient biocatalysts for carbohydrate synthesis: an exploration of natural and mutant diversityFrom1 Nov 2020 → TodayFunding: BOF - doctoral mandates
- Development of an inverting sucrose phosphorylase and its application for rare sugar production.From1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Retracing the steps of enzyme evolution: an exploration of ancestral sequence spaceFrom1 Oct 2020 → TodayFunding: FWO junior postdoctoral fellowship
- DeoxyBioCat: Unlocking Synthetic Biology of Deoxy Sugars via Redesigned Biocatalytic CascadesFrom1 Apr 2020 → TodayFunding: FWO research project
- Evolution at work: turning hydrolases into phosphorylases for the cost-efficient synthesis of glycosidic bonds.From1 Oct 2019 → TodayFunding: BOF - Doctoral projects
- Exploring the scope of nickel pincer as enzymatic cofactor:
engineering of gluconate epimerase towards the production of rare
sugars.From1 Jan 2018 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant
- Carbohydrate-based fine chemicals: Development of a glycosylation platform cell factory and optimization of downstream processing for the sustainable production of glycosidesFrom1 Jan 2018 → TodayFunding: H2020 - Leadership in enabling and industrial technologies (LEIT)
- GlycoProFit: Cost-efficient synthesis of health-promoting glycobiosesFrom1 Apr 2017 → TodayFunding: FWO Strategic Basic Research (SBO)
Publications
1 - 10 of 112 results
- Stereo-electronic control of reaction selectivity in short-chain dehydrogenases : decarboxylation, epimerization, and dehydration(2021)
Authors: Annika J.E. Borg, Koen Beerens, Martin Pfeiffer, Tom Desmet, Bernd Nidetzky
Pages: 43 - 52 - Expanding the enzyme repertoire for sugar nucleotide epimerization : the CDP-tyvelose 2-epimerase from Thermodesulfatator atlanticus for glucose/mannose interconversion(2021)
Authors: Christian Rapp, Stevie Van Overtveldt, Koen Beerens, Hansjörg Weber, Tom Desmet, Bernd Nidetzky
Number of pages: 1 - Synthesis, trehalase hydrolytic resistance and inhibition properties of 4-and 6-substituted trehalose derivatives(2020)
Authors: Shari Dhaene, Johan Van der Eycken, Koen Beerens, Jorick Franceus, Tom Desmet, Jurgen Caroen
Pages: 1964 - 1989 - GDP-altrose as novel product of GDP-mannose 3,5-epimerase : revisiting its reaction mechanism(2020)
Authors: Ophelia Gevaert, Stevie Van Overtveldt, Matthieu Da Costa, Koen Beerens, Tom Desmet
Pages: 1862 - 1868 - Synthesis of novel nitroxoline analogs with potent cathepsin B exopeptidase inhibitory activity(2020)
Authors: Tim Van de Walle, Marina Briand, Ana Mitrovic, Izidor Sosic, Stanislav Gobec, Janko Kos, Leentje Persoons, Dirk Daelemans, Steven De Jonghe, Zorica Ubiparip, et al.
Pages: 2477 - 2490 - Determinants of the nucleotide specificity in the carbohydrate epimerase family 1(2020)
Authors: Stevie Van Overtveldt, Matthieu Da Costa, Ophelia Gevaert, Henk-Jan Joosten, Koen Beerens, Tom Desmet
Number of pages: 1 - Fate of thymol and its monoglucosides in the gastrointestinal tract of piglets(2020)
Authors: Noémie Van Noten, Elout Van Liefferinge, Jeroen Degroote, Stefaan De Smet, Tom Desmet, Joris Michiels
Pages: 5241 - 5248 - Weaning affects the glycosidase activity towards phenolic glycosides in the gut of piglets(2020)
Authors: Noémie Van Noten, Elout Van Liefferinge, Jeroen Degroote, Stefaan De Smet, Tom Desmet, Joris Michiels
Pages: 1432 - 1443 - Novel insights into the existence of the putative UDP-glucuronate 5-epimerase specificity(2020)
Authors: Ophelia Gevaert, Stevie Van Overtveldt, Matthieu Da Costa, Koen Beerens, Tom Desmet
Number of pages: 1 - Oral microbiota display profound differential metabolic kinetics and community shifts upon incubation with sucrose, trehalose, kojibiose, and xylitol(2020)
Authors: Stanley Onyango, Nele De Clercq, Koen Beerens, John Van Camp, Tom Desmet, Tom Van de Wiele
Number of pages: 1