Researcher
Tom Desmet
- Keywords:biocatalysis, enzyme engineering, carbohydrate biotechnology
- Disciplines:Industrial molecular engineering of nucleic acids and proteins, Carbohydrates, Biocatalysis and enzyme technology
Affiliations
- Department of Biotechnology (Department)
Responsible
From1 Oct 2022 → Today - Department of Biotechnology (Department)
Member
From1 Oct 2022 → Today - Department of Biotechnology (Department)
Member
From1 Jan 2018 → Today - Department of Biochemical and microbial technology (Department)
Member
From1 Apr 2006 → 31 Dec 2017 - Department of Biochemistry and microbiology (Department)
Member
From1 Jan 2001 → 31 Mar 2006
Projects
1 - 10 of 35
- MyCOS - Synthetic biology for a sustainable conversion of fungal chitin-rich waste streams into valuable biobased chitooligosaccharides for plant healthFrom1 Jan 2022 → TodayFunding: FWO Thematic call for research projects in the field of bioeconomy
- Unlocking the specificity determinants in nucleotide sugar epimerasesFrom1 Nov 2021 → TodayFunding: FWO fellowships
- Evolution in practice: converting hydrolases and transferases into phosphorylasesFrom1 Nov 2021 → TodayFunding: FWO fellowships
- Apiose exploration: reaction mechanism and applications of apiose-specific glycosyltransferasesFrom1 Oct 2021 → TodayFunding: BOF - postdoctoral mandates
- Exploration of sucrose analogues enabled by enzyme and process engineeringFrom1 Oct 2021 → TodayFunding: BOF - projects
- Automated protein purification: an essential step towards further analyses and new applications.From1 Dec 2020 → TodayFunding: BOF - scientific equipment program
- Phosphorylases as cost-efficient biocatalysts for carbohydrate synthesis: an exploration of natural and mutant diversityFrom1 Nov 2020 → 31 Oct 2021Funding: BOF - doctoral mandates
- Development of an inverting sucrose phosphorylase and its application for rare sugar production.From1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Unlocking Synthetic Biology of Deoxy Sugars via Enzyme Engineering and Biocatalytic CascadesFrom1 Nov 2020 → TodayFunding: BOF - doctoral mandates
- Retracing the steps of enzyme evolution: an exploration of ancestral sequence spaceFrom1 Oct 2020 → TodayFunding: FWO junior postdoctoral fellowship
Publications
1 - 10 of 125
- In vitro stability and ex vivo absorption of thymol monoglucosides in the porcine gut(2022)
Authors: Noémie Van Noten, Elout Van Liefferinge, Jeroen Degroote, Stefaan De Smet, Tom Desmet, Joris Michiels
Number of pages: 1 - Metabolism and health effects of rare sugars in a CACO-2/HepG2 coculture model(2022)
Authors: Amar Daniël Emanuel Van Laar, Charlotte Grootaert, Filip Van Nieuwerburgh, Dieter Deforce, Tom Desmet, Koen Beerens, John Van Camp
Number of pages: 1 - Sweet biotechnology : enzymatic production and digestibility screening of novel kojibiose and nigerose analogues(2022)
Authors: Shari Dhaene, Amar Daniël Emanuel Van Laar, Marc De Doncker, Emma De Beul, Koen Beerens, Charlotte Grootaert, Jurgen Caroen, Johan Van der Eycken, John Van Camp, Tom Desmet
Pages: 3502 - 3511 - GDP-mannose 3,5-epimerase : a view on structure, mechanism, and industrial potential(2022)
Authors: Koen Beerens, Ophelia Gevaert, Tom Desmet
Number of pages: 1 - Kojibiose and trehalose long-term supplementation reveals significant metabolic differences and disaccharide dependent microbial community shift in a human gastrointestinal model(2021)
Authors: Stanley Onyango, Koen Beerens, Xinlin Jiao, Tom Desmet, Tom Van de Wiele
Number of pages: 1 - Stereo-electronic control of reaction selectivity in short-chain dehydrogenases : decarboxylation, epimerization, and dehydration(2021)
Authors: Annika J.E. Borg, Koen Beerens, Martin Pfeiffer, Tom Desmet, Bernd Nidetzky
Pages: 43 - 52 - U+03B2-Glucan phosphorylases in carbohydrate synthesis(2021)
Authors: Zorica Ubiparip, Marc De Doncker, Koen Beerens, Jorick Franceus, Tom Desmet
Pages: 4073 - 4087 - Exploration of GH94 sequence space for enzyme discovery reveals a novel glucosylgalactose phosphorylase specificity(2021)
Authors: Marc De Doncker, Chloé De Graeve, Jorick Franceus, Koen Beerens, Vladimír Kren, Helena Pelantová, Ronny Vercauteren, Tom Desmet
Pages: 3319 - 3325 - Structure-function relationships in NDP-sugar active SDR enzymes : fingerprints for functional annotation and enzyme engineering(2021)
Authors: Matthieu Da Costa, Ophelia Gevaert, Stevie Van Overtveldt, Joanna Lange, Henk-Jan Joosten, Tom Desmet, Koen Beerens
Number of pages: 1 - Expanding the enzyme repertoire for sugar nucleotide epimerization : the CDP-tyvelose 2-epimerase from Thermodesulfatator atlanticus for glucose/mannose interconversion(2021)
Authors: Christian Rapp, Stevie Van Overtveldt, Koen Beerens, Hansjörg Weber, Tom Desmet, Bernd Nidetzky
Number of pages: 1