Projects
A preclinical study to treat neuromuscular diseases caused by mutations in the small heat shock protein HSPB8 University of Antwerp
Investigating Functional and Behavioral Effects of Motor Behavior After Reversible Perturbations of Macaque Ventral Premotor Cortex Using Focal Ultrasound Neuromodulation and Chemogenetic Technique KU Leuven
Both the amygdala (AMY) and orbitofrontal cortex (OFC) has been thought to underlay flexible changes in behavior, guided by changes in stimulus-reward associations. Besides a role of AMY in valence coding and the formation of stimulus-reward associations and reversal learning when contingencies change, it has also been suggested that OFC mediates similar functions. Object-discrimination reversal (ODR) tasks are typically used to study ...
The role of stress granules in amyotrophic lateral sclerosis (ALS) KU Leuven
Recently, the group of C. Van Broeckhoven identified mutations in the vacuolar protein sorting 13 homolog C (VPS13C) (Philtjens et al., submitted). Studies on orthologous VPS13 proteins indicate essential roles in transport between the Golgi, lysosomes and the plasma membrane. We aim here to explicate the role of VPS13C in neuronal transport required to understand the effects of FTD-linked mutations. Additional Belgian FTD patients and ...
Interreg project "Memories". University of Antwerp
Prediction of conversion to Alzheimer's disease in Down syndrome: a behavioural and neurochemical approach. University of Antwerp
Elucidating the time course of semantic processing of written words, spoken words and pictures by means of multivariate MEG analysis KU Leuven
Language takes a very special place in human interactions. There are millions of words we can choose from to build a sentence in order to get exactly the right message across. Some words are very semantically similar, like a duck and a goose, some are vaguely similar because they share some features, like a duck and a vulture, and others are not similar at all, like a duck and an ice cream cone. Using functional MRI, we managed to identify ...