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Researcher
Zeger Debyser
- Disciplines:Laboratory medicine, Microbiology, Systems biology, Biomaterials engineering, Biological system engineering, Biomechanical engineering, Other (bio)medical engineering, Environmental engineering and biotechnology, Industrial biotechnology, Other biotechnology, bio-engineering and biosystem engineering
Affiliations
- Molecular Virology and Gene Therapy (Division)
Responsible
From1 Jan 2012 → Today - Molecular Virology and Gene Therapy (Division)
Member
From1 Jan 2013 → Today - Faculty of Medicine, Kulak Kortrijk Campus (Faculty)
Member
From1 Oct 2003 → 29 Feb 2008 - Faculty of Medicine (Faculty)
Member
From1 Oct 1999 → 30 Sep 2003
Projects
61 - 70 of 77
- Vevo 2100 micro-ultrasound machine with anesthesia platform and robotic arms for micromanipulation in small animals.From22 Jul 2010 → 21 Jan 2017Funding: Hercules - Small and Medium size research infrastructure
- Molecular mechanism of Transportin-SR2 mediated nuclear import of HIV.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Development of peptidomimetics for the inhibition of the interaction between HIV-integrase and the cellular co-factor LEDGF/p75.From1 Dec 2009 → 31 Aug 2012Funding: BOF - Other initiatives
- Development of a novel antiviral strategy directed against the nuclear import of HIV.From1 Oct 2009 → 13 Feb 2015Funding: FWO fellowships
- On the cell biology of retroviral integration.From1 Oct 2009 → 30 Sep 2013Funding: BOF - Concerted Research Project from 1994
- Cellular cofactors of HIV integrase as a basis for gene therapy.From1 Oct 2009 → 30 Jun 2010Funding: BOF - Other initiatives
- Nuclear import of HIV as a target for new antiviral therapyFrom1 Oct 2009 → 29 Jan 2014Funding: IWT personal funding - strategic basic research grants
- Development of inhibitors of integrase-LEDGF/P75 interaction.From23 Jul 2009 → 30 Jun 2011Funding: Other international institutions, not mentioned elsewhere
- Study of the development of peptidomimetics for the inhibition of the interaction of HIV-integrase and the cellular co-factor LEDGF/p75.From1 Jan 2009 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Laser scanning confocal microscope.From20 Oct 2008 → 19 Apr 2015Funding: Hercules - Small and Medium size research infrastructure
Publications
1 - 10 of 305
- New latency-promoting agents for a block-and-lock functional cure strategy.(2024)
Authors: Eline Pellaers, Zeger Debyser
- The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function(2024)
Authors: Siska Van Belle, Zeger Debyser
- The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture(2023)
Authors: Anne Bruggemans, Zeger Debyser
- Particle-based phasor-FLIM-FRET resolves protein-protein interactions inside single viral particles(2023)
Authors: Quinten Coucke, Guillermo Solís Fernández, Johan Hofkens, Zeger Debyser, Jelle Hendrix
- Development of novel therapeutic strategies for rare CFTR mutations causing severe cystic fibrosis(2023)
Authors: Marjolein Ensinck, Zeger Debyser, Christiane De Boeck, Marianne Carlon
- Determinants of Retroviral Integration and Implications for Gene Therapeutic MLV-Based Vectors and for a Cure for HIV-1 Infection(2023)
Authors: Eline Pellaers, Anayat Bhat, Frauke Christ, Zeger Debyser
- Development of a new therapeutic strategy for the treatment of MLL-rearranged acute leukemia(2022)
Authors: Siska Van Belle, Zeger Debyser, Frauke Christ
- Single-Cell Imaging Shows That the Transcriptional State of the HIV-1 Provirus and Its Reactivation Potential Depend on the Integration Site(2022)
Authors: Zeger Debyser
- Design, synthesis, in silico studies, and antiproliferative evaluations of novel indolin-2-one derivatives containing 3-hydroxy-4-pyridinone fragment(2022)
Authors: Siska Van Belle, Zeger Debyser, Frauke Christ
- Expansion microscopy allows high resolution single cell analysis of epigenetic readers(2022)
Authors: Boris Louis, Susana Neves Rocha, Thierry Voet, Zeger Debyser, Johan Hofkens
Patents
1 - 9 of 9
- Functional cure of retroviral infection (Inventor)
- Functional cure of retroviral infection (Inventor)
- Thieno[2,3-b]pyridine derivatives as viral replication inhibitors (Inventor)
- Functional cure of retroviral infection (Inventor)
- Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors (Inventor)
- ;Antiviral compounds (Inventor)
- THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS (Inventor)
- NOVEL ANTIVIRAL COMPOUNDS (Inventor)
- VIRAL REPLICATION INHIBITORS (Inventor)