Researcher
Sofie Demeyer
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Systems biology
- See also: Sofie Demeyer (Flanders Institute for Biotechnology)
Affiliations
- Cools Lab (Research group)
Member
From1 Jan 2017 → Today - Laboratory of Molecular Biology of Leukemia (VIB-KU Leuven) (Division)
Member
From12 May 2014 → Today
Projects
1 - 1 of 1
- Combining CRISPR screening and single-cell RNA sequencing to unravel the mechanisms of T-cell acute lymphoblastic leukemiaFrom1 Oct 2019 → TodayFunding: FWO fellowships, BOF - doctoral mandates
Publications
11 - 20 of 35
- Monitoring of Leukemia Clones in B-cell Acute Lymphoblastic Leukemia at Diagnosis and During Treatment by Single-cell DNA Amplicon Sequencing(2022)
Authors: Sarah Meyers, Jolien De Bie, Lucienne Michaux, Barbara Dewaele, Nancy Boeckx, Anne Uyttebroeck, Kim De Keersmaecker, Johan Maertens, Heidi Segers, Jan Cools, et al.
- Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma(2021)
Authors: Sofie Demeyer, Jan Cools
Pages: 1040 - 1052 - Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia(2021)
Authors: Quentin Van Thillo, Jolien De Bie, Sofie Demeyer, Heidi Segers, Nancy Boeckx, Anne Uyttebroeck, Jan Cools
- Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified(2021)
Authors: Koen Debackere, Lukas Marcelis, Sofie Demeyer, Marlies Vanden Bempt, Gregor Verhoef, Lucienne Michaux, Thomas Tousseyn, Jan Cools, Daan Dierickx
- Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia(2021)
Authors: Sofie Demeyer, Inge Govaerts, Jolien De Bie, Lucienne Michaux, Johan Maertens, Anne Uyttebroeck, Kim De Keersmaecker, Nancy Boeckx, Heidi Segers, Jan Cools
Pages: 801 - 811 - The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia(2020)
Authors: Delphine Verbeke, Sofie Demeyer, Jolien De Bie, Anne Uyttebroeck, Nancy Boeckx, Kim De Keersmaecker, Johan Maertens, Heidi Segers, Jan Cools
Pages: 5747 - 5758 - Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia(2019)
Authors: Michaël Broux, Cristina PRIETO FERNANDEZ, Sofie Demeyer, Marlies Vanden Bempt, Inge Lodewijckx, Roel Vandepoel, Jan Cools
Pages: 1323 - 1336 - Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition(2019)
Authors: Charles De Bock, Inge Lodewijckx, Delphine Verbeke, David Nittner, Sofie Demeyer, James Dooley, Adrian Liston, Jan Cools, Bart De Strooper
- The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells(2018)
Authors: Aleksandra Brajic, Simon Bornschein, Sofie Demeyer, Jan Cools, James Dooley, Susan Schlenner, Adrian Liston
- The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models(2018)
Authors: Rocco Stirparo, Sofie Demeyer, Charles De Bock, Mardelle Atkins, Georg Halder, Bassem Hassan, Jan Cools