Researcher
Kim De Keersmaecker
- Disciplines:Cancer biology
Affiliations
- Laboratory for Disease Mechanisms in Cancer (Division)
Responsible
From1 Oct 2016 → Today - Laboratory for Disease Mechanisms in Cancer (Division)
Member
From1 Oct 2014 → Today - Department of Human Genetics (Department)
Member
From1 Oct 2013 → 30 Sep 2014 - Laboratory of Molecular Biology of Leukemia (VIB-KU Leuven) (Division)
Member
From1 Mar 2009 → 30 Sep 2015
Projects
1 - 10 of 42
- Raising the voice of silent mutations in cancerFrom1 Oct 2023 → TodayFunding: BOF - postdoctoral mandates
- Deregulated mRNA transcription and protein translation in the transformation of normal T-cells to malignant cells.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Serine/glycine synthesis addiction in acute lymphoblastic leukemia and resulting therapeutic opportunitiesFrom4 Jul 2021 → TodayFunding: FWO fellowships
- Serine/glycine synthesis addiction in acute lymphoblastic leukemia and resulting therapeutic opportunitiesFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- VyCAP single cell isolation platform for high-quality single-cell analysisFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- Role of -1 programmed ribosomal frameshifting dysregulation on the JAK2 oncogeneFrom25 Jul 2020 → TodayFunding: FWO fellowships
- Silent mutations in cancerFrom1 May 2020 → TodayFunding: H2020 - Frontier Research (ERC)
- The role of NKX2-1 in T-cell acute lymphoblastic leukemia and NKX2-1 cooperation with the ribosomal RPL10 R98S and NOTCH1 mutations.From1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Role of PTEN dysregulation downstream of ribosomal protein RPL5/RPL11 lesions in cancer.From1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Fidelity of translation in healthy agingFrom26 Sep 2019 → 26 Sep 2023Funding: BOF - doctoral mandates
Publications
1 - 10 of 90
- Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer (12 FEB, 10.1038/s41416-023-02553-y, 2024 )(2024)
Authors: Kim De Keersmaecker, Maarten Lambrecht, Kim Kampen
- Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer(2024)
Authors: Kim De Keersmaecker, Maarten Lambrecht, Kim Kampen
Pages: 568 - 584 - Toward more accurate preclinical glioblastoma modeling: Reverse translation of clinical standard of care in a glioblastoma mouse model.(2024)
Authors: Yani Berckmans, Kim De Keersmaecker, An Coosemans
Pages: 381 - 397 - Drivers of de novo Serine/Glycine synthesis in acute leukemia(2023)
Authors: Paulien Verstraete, Kim De Keersmaecker, Kim Kampen
Pages: 2145 - 2146 - APEX1 Nuclease and Redox Functions are Both Essential for Adult Mouse Hematopoietic Stem and Progenitor Cells(2023)
Authors: Samantha Zaunz, Lukas Lauwereins, Kim De Keersmaecker, Catherine Verfaillie
Pages: 2052 - 2072 - Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer(2023)
Authors: Elien Heylen, Paulien Verstraete, Linde Van Aerschot, Tom Venken, David Nittner, Anne Uyttebroeck, Heidi Segers, Diether Lambrechts, Jan Cools, Kim De Keersmaecker, et al.
Pages: 1862 - 1878 - Oncogenic drivers and therapeutic targeting of serine and glycine synthesis in cancer(2023)
Authors: Elien Heylen, Kim De Keersmaecker, Kim Kampen
- SNPs Ability to Influence Disease Risk: Breaking the Silence on Synonymous Mutations in Cancer(2022)
Authors: Xander Janssens, Daniele Pepe, Kim De Keersmaecker
Pages: 77 - 96Number of pages: 20 - HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia(2022)
Authors: Kim De Keersmaecker, Veerle Labarque
Pages: 3111 - 3126 - Optimizing the diagnostic workflow for acute lymphoblastic leukemia by optical genome mapping(2022)
Authors: Jolien De Bie, Sofie Demeyer, Jan Cools, Kim De Keersmaecker, Joris Vermeesch, Johan Maertens, Heidi Segers, Lucienne Michaux, Barbara Dewaele
Pages: 548 - 561
Patents
1 - 3 of 3