Researcher
Simon Bornschein
- Disciplines:Systems biology, Molecular and cell biology, Immunology
Affiliations
- Adaptive Immunology (Lab)
Member
From1 Nov 2012 → 31 Mar 2018
Projects
1 - 1 of 1
- The role of long-non-coding RNA in regulatory T cell development and functionFrom1 Mar 2013 → 30 Sep 2018Funding: FWO fellowships
Publications
1 - 10 of 17
- Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection(2019)
Authors: Youlia Lampi, Dominique Van Looveren, Simon Bornschein, Zeger Debyser, Rik Gijsbers
- Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia (vol 32, pg 788, 2018)(2018)
Authors: Sandrine Degryse, CE de Bock, S Demeyer, Inge Govaerts, Simon Bornschein, Delphine Verbeke, K Jacobs, S Binos, DA Skerrett-Byrne, HC Murray, et al.
Pages: 2731 - 2731 - A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA plus and total RNA sequencing(2018)
Authors: Simon Bornschein, Charles De Bock, Stein Aerts, Jan Cools
Pages: E585 - E589 - Malt1 self-cleavage is critical for regulatory Tcell homeostasis and anti-tumor immunity in mice(2018)
Authors: Rocco Stirparo, Youlia Lampi, Delphine Verbeke, Jan Cools, Peter Marynen, Charles De Bock, Simon Bornschein
Pages: 1728 - 1738 - The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells(2018)
Authors: Aleksandra Brajic, Simon Bornschein, Sofie Demeyer, Jan Cools, James Dooley, Susan Schlenner, Adrian Liston
- Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia(2018)
Authors: Marlies Vanden Bempt, Sofie Demeyer, Michaël Broux, Jolien De Bie, Simon Bornschein, Ellen Geerdens, Charles De Bock, Jan Cools
Pages: 271 - + - Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T cell model system(2018)
Authors: Simon Bornschein, Sofie Demeyer, Rocco Stirparo, Carmen Vicente, Ellen Geerdens, Bart Ghesquière, Stein Aerts, Jan Cools, Charles De Bock
Pages: 941 - 951 - Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia(2018)
Authors: Sandrine Degryse, Charles De Bock, Sofie Demeyer, Inge Govaerts, Simon Bornschein, Delphine Verbeke, Jan Cools
Pages: 788 - 800 - The T-cell leukemia associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling(2018)
Authors: Tiziana Girardi, Stijn Vereecke, Sergey Sulima, Laura Fancello, Ellen Geerdens, Carmen Vicente, Simon Bornschein, Jan Cools, Kim Kampen, Kim De Keersmaecker
Pages: 809 - 819 - The T-cell leukemia associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling(2018)
Authors: Tiziana Girardi, Stijn Vereecke, Sergey Sulima, Y Khan, Laura Fancello, JW Briggs, C Schwab, JO de Beeck, J Verbeeck, Jonathan Royaert, et al.
Pages: 809 - 819