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Researcher
Inge Govaerts
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Systems biology
- See also: Inge Govaerts (Flanders Institute for Biotechnology)
Affiliations
- Cools Lab (Research group)
Member
From1 Jan 2017 → 31 Dec 2021 - Laboratory of Molecular Biology of Leukemia (VIB-KU Leuven) (Division)
Member
From1 Aug 2016 → Today
Projects
1 - 1 of 1
- The oncogenic JAK-STAT signaling network in T-cell acute lymphoblastic leukemia and its link with epigenetic changes and RNA metabolismFrom1 Aug 2016 → 21 Dec 2023Funding: FWO fellowships
Publications
1 - 6 of 6
- Identification of novel targets for treatment in T-cell acute lymphoblastic leukemia(2023)
Authors: Inge Govaerts, Jan Cools
- PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia(2021)
Authors: Inge Govaerts, Charlien Vandersmissen, David Nittner, Johan Maertens, Nancy Boeckx, Kim De Keersmaecker, Heidi Segers, Jan Cools
- Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia(2021)
Authors: Sofie Demeyer, Inge Govaerts, Jolien De Bie, Lucienne Michaux, Johan Maertens, Anne Uyttebroeck, Kim De Keersmaecker, Nancy Boeckx, Heidi Segers, Jan Cools
Pages: 801 - 811 - JAK/STAT Pathway Mutations in T-ALL, Including the STAT5B N642H Mutation, are Sensitive to JAK1/JAK3 Inhibitors(2019)
Authors: Inge Govaerts, Jan Cools
- Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia (vol 32, pg 788, 2018)(2018)
Authors: Sandrine Degryse, CE de Bock, S Demeyer, Inge Govaerts, Simon Bornschein, Delphine Verbeke, K Jacobs, S Binos, DA Skerrett-Byrne, HC Murray, et al.
Pages: 2731 - 2731 - Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia(2018)
Authors: Sandrine Degryse, Charles De Bock, Sofie Demeyer, Inge Govaerts, Simon Bornschein, Delphine Verbeke, Jan Cools
Pages: 788 - 800